CI-1007


SMILES C1=C(c2ccccc2)CCN(C[C@@H]2CCC=C(c3ccccc3)C2)C1
InChIKey XBGWTWPYCTZIIE-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 329.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.04 7.04 7.04 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.28 7.88 8.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.78 7.78 7.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.59 7.75 8.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.28 7.28 7.28 ChEMBL