CHEMBL473898


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCN2CCCC2)CN3c2ccccc2)c2ccccc21
InChIKey VOSNJKFVBDSLTN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 486.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.85 8.85 8.85 ChEMBL
δ OPRD Human Opioid A pKi 5.91 5.91 5.91 ChEMBL
κ OPRK Human Opioid A pKi 6.77 6.77 6.77 ChEMBL
μ OPRM Human Opioid A pKi 7.16 7.16 7.16 ChEMBL
δ OPRD Human Opioid A pKi 5.91 5.91 5.91 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.85 8.85 8.85 PDSP Ki database
κ OPRK Human Opioid A pKi 6.77 6.77 6.77 PDSP Ki database
μ OPRM Human Opioid A pKi 7.16 7.16 7.16 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database