CHEMBL476109


SMILES O=C(CCCN1C2CCC1CN(c1ccc(Cl)cc1)CC2)c1ccc(F)cc1
InChIKey YWOYXYWGFUHWBM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.99 5.99 5.99 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.75 6.75 6.75 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.26 6.26 6.26 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.99 5.99 5.99 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database