CHEMBL4596780


SMILES CC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey LYFQHKXGGDVXCQ-YATWDLPUSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 6
Rotatable bonds 20
Molecular weight (Da) 851.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.15 7.15 7.15 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.95 8.95 8.95 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.56 7.56 7.56 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.1 10.1 10.1 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.85 8.85 8.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database