CHEMBL4863347


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(Cl)cc1
InChIKey HLUKJXBXVAJVDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 394.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.07 5.07 5.07 ChEMBL
H2 HRH2 Human Histamine A pKi 7.33 7.33 7.33 ChEMBL
H1 HRH1 Human Histamine A pKi 5.35 5.35 5.35 ChEMBL
H3 HRH3 Human Histamine A pKi 4.75 4.75 4.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database