CHEMBL489582


SMILES O=c1ccc(-n2ccnc2)nn1CCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1
InChIKey AQFHIZYLJBPOKQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database