CHEMBL4802611


SMILES Cc1cc(/C=C/c2cc3c4c(c2)CCCN4CCC3)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey MMTRDAGHFRJWIB-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 806.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.9 6.9 6.9 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.57 8.57 8.57 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.2 7.2 7.2 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.72 8.96 9.19 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.32 8.67 9.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database