BMY-14802


SMILES Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(cn1)F)O
InChIKey ZXUYYZPJUGQHLQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 5.08 5.19 5.31 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.5 6.5 6.5 ChEMBL
D2 DRD2 Mouse Dopamine A pIC50 5.61 5.61 5.61 ChEMBL