Biased Signaling Atlas

Ligand source activities (1 row/activity)

Ligand				Receptor			Assay information								Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	UniProt	IUPHAR	Species	p-value (-log)	Activity Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	172198	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	2504	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	45266664	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	5272	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	CHEMBL408403	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	DB11842	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	172198	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	2504	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	45266664	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	5272	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	CHEMBL408403	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	DB11842	400	40	AGTR1	AT₁ receptor	Human	9.3	pEC50	=	9.3	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.5b01495
	127030943	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787243	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787375	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787700	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	127030943	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787243	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787375	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787700	138400	0	AGTR1	AT₁ receptor	Human	9.0	pEC50	=	9.0	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1216	35	15	14	-0.7	CCC(=O)NCCCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	172198	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	2504	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	45266664	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	5272	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	CHEMBL408403	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	DB11842	400	40	AGTRA	AT₁ receptor	Rat	8.9	pEC50	=	8.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	127029976	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3786145	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3787767	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	127029976	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3786145	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3787767	138422	0	AGTR1	AT₁ receptor	Human	8.9	pEC50	=	8.9	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1160	33	15	14	-1.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	155540547	171679	0	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	13	-2.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(F)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4483576	171679	0	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	13	-2.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(F)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155539027	171980	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	944	26	13	12	-1.8	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4514079	171980	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	944	26	13	12	-1.8	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155541295	172167	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4518318	172167	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155547844	172853	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	942	26	14	13	-2.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4535678	172853	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	942	26	14	13	-2.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155564502	174414	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4572408	174414	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155565112	174652	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1081	26	13	12	-0.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4577692	174652	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1081	26	13	12	-0.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155546362	172706	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	26	12	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4532075	172706	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	26	12	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155568289	175279	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	898	26	11	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4592000	175279	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	898	26	11	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155557139	173699	0	AGTR1	AT₁ receptor	Human	5.0	pEC50	=	5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	980	26	12	12	-0.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4556070	173699	0	AGTR1	AT₁ receptor	Human	5.0	pEC50	=	5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	980	26	12	12	-0.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155520024	172401	0	AGTRA	AT₁ receptor	Rat	5.0	pEC50	=	5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	27	13	12	-1.6	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4524570	172401	0	AGTRA	AT₁ receptor	Rat	5.0	pEC50	=	5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	27	13	12	-1.6	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155557139	173699	0	AGTRA	AT₁ receptor	Rat	5.0	pEC50	=	5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	980	26	12	12	-0.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4556070	173699	0	AGTRA	AT₁ receptor	Rat	5.0	pEC50	=	5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	980	26	12	12	-0.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL938	207999	18	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	11943	3635	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	145925549	3635	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	CHEMBL4438122	3635	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	155558059	173838	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	CHEMBL4559239	173838	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	155544988	172597	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	853	24	12	11	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1C(N)=O	nan
	CHEMBL4529051	172597	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	853	24	12	11	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1C(N)=O	nan
	155541440	172176	0	AGTR1	AT₁ receptor	Human	7.9	pEC50	=	7.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	CHEMBL4518530	172176	0	AGTR1	AT₁ receptor	Human	7.9	pEC50	=	7.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	155541440	172176	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	CHEMBL4518530	172176	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	155540033	172046	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	CHEMBL4515768	172046	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	155541125	172121	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	CHEMBL4517561	172121	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	155540470	171634	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.3	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4482867	171634	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.3	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155559120	173941	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-1.8	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4561769	173941	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-1.8	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155564502	174414	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4572408	174414	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	54696627	97653	0	AGTR1	AT₁ receptor	Bovine	5.9	pEC50	=	5.9	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	486	5	2	7	5.0	Cc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2n1	10.1016/S0960-894X(01)81134-3
	CHEMBL27511	97653	0	AGTR1	AT₁ receptor	Bovine	5.9	pEC50	=	5.9	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	486	5	2	7	5.0	Cc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2n1	10.1016/S0960-894X(01)81134-3
	54726669	98570	0	AGTR1	AT₁ receptor	Bovine	5.9	pEC50	=	5.9	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	461	5	2	6	4.6	O=c1c(-c2ccccc2)c(O)c2c(n1Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)CCC2	10.1016/S0960-894X(01)81134-3
	CHEMBL281887	98570	0	AGTR1	AT₁ receptor	Bovine	5.9	pEC50	=	5.9	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	461	5	2	6	4.6	O=c1c(-c2ccccc2)c(O)c2c(n1Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)CCC2	10.1016/S0960-894X(01)81134-3
	155539027	171980	0	AGTR1	AT₁ receptor	Human	7.9	pEC50	=	7.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	944	26	13	12	-1.8	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4514079	171980	0	AGTR1	AT₁ receptor	Human	7.9	pEC50	=	7.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	944	26	13	12	-1.8	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155541295	172167	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4518318	172167	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155547428	172770	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4533618	172770	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155550799	173428	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4549405	173428	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155543091	172335	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4522246	172335	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155520014	172391	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	27	14	13	-1.9	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4524300	172391	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	27	14	13	-1.9	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL2028943	202659	0	AGTRA	AT₁ receptor	Rat	7.9	pEC50	=	7.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	CHEMBL2370909	203471	0	AGTRA	AT₁ receptor	Rat	6.9	pEC50	=	6.9	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155542907	172332	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	CHEMBL4522038	172332	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	155563676	174498	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4574199	174498	0	AGTR1	AT₁ receptor	Human	5.9	pEC50	=	5.9	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155540639	172089	0	AGTRA	AT₁ receptor	Rat	5.9	pEC50	=	5.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4516768	172089	0	AGTRA	AT₁ receptor	Rat	5.9	pEC50	=	5.9	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL2392353	203929	4	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	3082475	3637	6	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	6902	3637	6	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4297447	3637	6	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	DB12199	3637	6	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155568804	175272	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4591857	175272	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL2028943	202659	0	AGTR1	AT₁ receptor	Human	6.8	pEC50	=	6.8	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155541240	172172	0	AGTR1	AT₁ receptor	Human	6.8	pEC50	=	6.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	928	26	12	11	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4518420	172172	0	AGTR1	AT₁ receptor	Human	6.8	pEC50	=	6.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	928	26	12	11	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155563538	174454	0	AGTR1	AT₁ receptor	Human	6.8	pEC50	=	6.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	CHEMBL4573250	174454	0	AGTR1	AT₁ receptor	Human	6.8	pEC50	=	6.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	155554529	173788	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(F)cc(O)cc1F)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4557984	173788	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(F)cc(O)cc1F)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	10533900	175122	2	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	CHEMBL4588454	175122	2	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	155544246	172521	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	887	24	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4527484	172521	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	887	24	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155553003	173230	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	CHEMBL4544308	173230	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	155561477	174346	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	811	22	12	11	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4570840	174346	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	811	22	12	11	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155562469	174375	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	29	12	12	-1.1	C=CCOc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(=O)O)[C@@H](C)CC)cc1	nan
	CHEMBL4571382	174375	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	29	12	12	-1.1	C=CCOc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(=O)O)[C@@H](C)CC)cc1	nan
	155553930	174594	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4576650	174594	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155553930	174594	0	AGTRA	AT₁ receptor	Rat	4.8	pEC50	=	4.8	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4576650	174594	0	AGTRA	AT₁ receptor	Rat	4.8	pEC50	=	4.8	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155551279	173141	0	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assayAgonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay	ChEMBL	877	29	13	12	-2.3	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)CN[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	10.1021/acs.jmedchem.8b00435
	CHEMBL4542269	173141	0	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assayAgonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay	ChEMBL	877	29	13	12	-2.3	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)CN[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	10.1021/acs.jmedchem.8b00435
	3082475	3637	6	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	6902	3637	6	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4297447	3637	6	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	DB12199	3637	6	AGTR1	AT₁ receptor	Human	7.8	pEC50	=	7.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	70538373	174651	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	840	23	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C	nan
	CHEMBL4577691	174651	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	840	23	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C	nan
	155554865	173509	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4551317	173509	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	54726671	93946	0	AGTR1	AT₁ receptor	Bovine	5.8	pEC50	=	5.8	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	471	5	2	6	5.3	O=c1c(-c2ccccc2)c(O)c2ccccc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)81134-3
	CHEMBL25226	93946	0	AGTR1	AT₁ receptor	Bovine	5.8	pEC50	=	5.8	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	471	5	2	6	5.3	O=c1c(-c2ccccc2)c(O)c2ccccc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)81134-3
	155560095	174077	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	26	14	13	-2.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4564950	174077	0	AGTRA	AT₁ receptor	Rat	7.8	pEC50	=	7.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	26	14	13	-2.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155563538	174454	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	CHEMBL4573250	174454	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	155565687	174736	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4579604	174736	0	AGTRA	AT₁ receptor	Rat	6.8	pEC50	=	6.8	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155556507	173641	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4554466	173641	0	AGTR1	AT₁ receptor	Human	5.8	pEC50	=	5.8	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	54726670	93291	0	AGTR1	AT₁ receptor	Bovine	5.8	pEC50	=	5.8	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	491	7	2	5	6.2	CCOc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	CHEMBL24842	93291	0	AGTR1	AT₁ receptor	Bovine	5.8	pEC50	=	5.8	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	491	7	2	5	6.2	CCOc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	155560463	174195	0	AGTRA	AT₁ receptor	Rat	7.7	pEC50	=	7.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	CHEMBL4567667	174195	0	AGTRA	AT₁ receptor	Rat	7.7	pEC50	=	7.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	155540033	172046	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	CHEMBL4515768	172046	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	155553003	173230	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	CHEMBL4544308	173230	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	155554865	173509	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4551317	173509	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155564502	174414	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4572408	174414	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	2296	33	30	27	-2.1	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	127029977	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3786986	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3787768	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	127029977	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3786986	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	CHEMBL3787768	138423	0	AGTR1	AT₁ receptor	Human	8.7	pEC50	=	8.7	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1220	37	15	16	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN/C(N)=N/C(=O)NCCOCCOCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O	10.1021/acs.jmedchem.5b01495
	127031545	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787379	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787701	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	127031545	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787379	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	CHEMBL3787701	138401	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assayAgonist activity at human AT1 receptor transfected in CHO cells co-expressing Galpha16-mtAEQ assessed as induction of intracellular Ca2+ mobilization by bioluminescence assay	ChEMBL	1276	39	15	16	-1.4	CCC(=O)NCCOCCOCCNC(=O)/N=C(\N)NCCC[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)[C@@H](C)CC)C(C)C	10.1021/acs.jmedchem.5b01495
	172198	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	2504	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	45266664	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	5272	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	CHEMBL408403	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	DB11842	400	40	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	155541440	172176	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	CHEMBL4518530	172176	0	AGTR1	AT₁ receptor	Human	8.6	pEC50	=	8.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	155560463	174195	0	AGTR1	AT₁ receptor	Human	7.7	pEC50	=	7.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	CHEMBL4567667	174195	0	AGTR1	AT₁ receptor	Human	7.7	pEC50	=	7.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	10533900	175122	2	AGTRA	AT₁ receptor	Rat	7.7	pEC50	=	7.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	CHEMBL4588454	175122	2	AGTRA	AT₁ receptor	Rat	7.7	pEC50	=	7.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	155551762	173164	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	26	13	12	-2.2	CCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4542709	173164	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	26	13	12	-2.2	CCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155556507	173641	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4554466	173641	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155552995	173266	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	27	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4545399	173266	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	27	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155556530	173666	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4555119	173666	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	155568109	175191	0	AGTR1	AT₁ receptor	Human	5.7	pEC50	=	5.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-2.0	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4590381	175191	0	AGTR1	AT₁ receptor	Human	5.7	pEC50	=	5.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-2.0	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL2392353	203929	4	AGTR1	AT₁ receptor	Human	7.7	pEC50	=	7.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155556530	173666	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4555119	173666	0	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	11944	3636	0	AGTR1	AT₁ receptor	Human	5.7	pEC50	=	5.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155552190	3636	0	AGTR1	AT₁ receptor	Human	5.7	pEC50	=	5.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4544228	3636	0	AGTR1	AT₁ receptor	Human	5.7	pEC50	=	5.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155540470	171634	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.3	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4482867	171634	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.3	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155553311	173287	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4546162	173287	0	AGTRA	AT₁ receptor	Rat	5.7	pEC50	=	5.7	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	154573825	175142	4	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4588946	175142	4	AGTR1	AT₁ receptor	Human	6.7	pEC50	=	6.7	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	155563538	174454	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	CHEMBL4573250	174454	0	AGTRA	AT₁ receptor	Rat	6.7	pEC50	=	6.7	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	925	26	13	12	-2.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O	nan
	54726676	98527	0	AGTR1	AT₁ receptor	Bovine	5.7	pEC50	=	5.7	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	501	6	2	7	5.3	COc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	CHEMBL28162	98527	0	AGTR1	AT₁ receptor	Bovine	5.7	pEC50	=	5.7	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	501	6	2	7	5.3	COc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	155540328	172057	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	CHEMBL4516066	172057	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	155559104	173961	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4562270	173961	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155554865	173509	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4551317	173509	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	2269	27	21	24	3.8	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155547428	172770	0	AGTR1	AT₁ receptor	Human	7.6	pEC50	=	7.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4533618	172770	0	AGTR1	AT₁ receptor	Human	7.6	pEC50	=	7.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155568318	175254	0	AGTR1	AT₁ receptor	Human	7.6	pEC50	=	7.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4591448	175254	0	AGTR1	AT₁ receptor	Human	7.6	pEC50	=	7.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155559827	174070	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	970	27	13	14	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4564617	174070	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	970	27	13	14	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155540328	172057	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	CHEMBL4516066	172057	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	155565112	174652	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1081	26	13	12	-0.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4577692	174652	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1081	26	13	12	-0.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155553479	173332	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4547423	173332	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155558003	173848	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4559421	173848	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155558784	173931	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4561366	173931	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155547428	172770	0	AGTRA	AT₁ receptor	Rat	4.6	pEC50	=	4.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4533618	172770	0	AGTRA	AT₁ receptor	Rat	4.6	pEC50	=	4.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	959	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155566196	174899	0	AGTRA	AT₁ receptor	Rat	4.6	pEC50	=	4.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4583284	174899	0	AGTRA	AT₁ receptor	Rat	4.6	pEC50	=	4.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155558428	173884	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4560224	173884	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	11944	3636	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	155552190	3636	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	CHEMBL4544228	3636	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	155540639	172089	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4516768	172089	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155553479	173332	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4547423	173332	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155558428	173884	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4560224	173884	0	AGTRA	AT₁ receptor	Rat	7.6	pEC50	=	7.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155553479	173332	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4547423	173332	0	AGTR1	AT₁ receptor	Human	6.6	pEC50	=	6.6	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	949	26	14	13	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155543972	174170	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	13	12	-1.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4567103	174170	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	13	12	-1.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155567790	175205	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	877	24	13	12	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4590589	175205	0	AGTRA	AT₁ receptor	Rat	6.6	pEC50	=	6.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	877	24	13	12	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155556507	173641	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4554466	173641	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	910	26	12	11	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	130762	97554	7	AGTR1	AT₁ receptor	Bovine	5.6	pEC50	=	5.6	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	398	8	2	4	4.8	CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C(=O)O)cc1	10.1016/S0960-894X(01)81134-3
	CHEMBL274447	97554	7	AGTR1	AT₁ receptor	Bovine	5.6	pEC50	=	5.6	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	398	8	2	4	4.8	CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C(=O)O)cc1	10.1016/S0960-894X(01)81134-3
	155568109	175191	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-2.0	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4590381	175191	0	AGTRA	AT₁ receptor	Rat	5.6	pEC50	=	5.6	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-2.0	CN[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL77838	207970	1	AGTR1	AT₁ receptor	Human	8.5	pEC50	=	8.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(C)C)C(=O)O	nan
	CHEMBL77838	207970	1	AGTRA	AT₁ receptor	Rat	8.5	pEC50	=	8.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(C)C)C(=O)O	nan
	155552475	173206	0	AGTR1	AT₁ receptor	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4543860	173206	0	AGTR1	AT₁ receptor	Human	8.4	pEC50	=	8.4	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155558428	173884	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4560224	173884	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	897	26	15	12	-3.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155542907	172332	0	AGTRA	AT₁ receptor	Rat	6.5	pEC50	=	6.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	CHEMBL4522038	172332	0	AGTRA	AT₁ receptor	Rat	6.5	pEC50	=	6.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	155560095	174077	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	26	14	13	-2.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4564950	174077	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	26	14	13	-2.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155548506	172909	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	13	12	-1.9	CN[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	CHEMBL4536886	172909	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	13	12	-1.9	CN[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	155569246	175335	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	869	25	13	12	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4593310	175335	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	869	25	13	12	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155568804	175272	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4591857	175272	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL2028943	202659	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155568318	175254	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4591448	175254	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155543091	172335	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4522246	172335	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155550799	173428	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4549405	173428	0	AGTR1	AT₁ receptor	Human	7.5	pEC50	=	7.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	26	13	12	-1.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155540639	172089	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4516768	172089	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155544988	172597	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	853	24	12	11	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1C(N)=O	nan
	CHEMBL4529051	172597	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	853	24	12	11	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1C(N)=O	nan
	155552475	173206	0	AGTRA	AT₁ receptor	Rat	6.5	pEC50	=	6.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4543860	173206	0	AGTRA	AT₁ receptor	Rat	6.5	pEC50	=	6.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155565687	174736	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4579604	174736	0	AGTR1	AT₁ receptor	Human	6.5	pEC50	=	6.5	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155556530	173666	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4555119	173666	0	AGTRA	AT₁ receptor	Rat	7.5	pEC50	=	7.5	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	911	25	13	12	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O)C(C)C)C(C)C	nan
	1610	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	3941	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	3961	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	590	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	CHEMBL191	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	DB00678	2209	80	AGTR1	AT₁ receptor	Bovine	6.5	pEC50	=	6.5	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	422	8	2	6	4.3	CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl	10.1016/S0960-894X(01)81134-3
	155561376	174828	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	917	28	12	11	-1.4	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(N)=O	nan
	CHEMBL4581718	174828	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	917	28	12	11	-1.4	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(N)=O	nan
	155563973	174515	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	941	27	14	13	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4574655	174515	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	941	27	14	13	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155541295	172167	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4518318	172167	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	12	12	-2.0	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	145925550	174625	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	903	24	13	12	-2.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4577270	174625	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	903	24	13	12	-2.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155539838	172051	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4515848	172051	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	11943	3635	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	145925549	3635	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4438122	3635	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155540033	172046	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	CHEMBL4515768	172046	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	155520014	172391	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	27	14	13	-1.9	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4524300	172391	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	975	27	14	13	-1.9	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL312754	204624	13	AGTRA	AT₁ receptor	Rat	8.3	pEC50	=	8.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155548506	172909	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	13	12	-1.9	CN[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	CHEMBL4536886	172909	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	926	25	13	12	-1.9	CN[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	155548148	172870	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	943	26	14	14	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4535997	172870	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	943	26	14	14	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155554529	173788	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(F)cc(O)cc1F)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4557984	173788	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(F)cc(O)cc1F)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155566196	174899	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4583284	174899	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155558003	173848	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4559421	173848	0	AGTRA	AT₁ receptor	Rat	5.4	pEC50	=	5.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155541125	172121	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	CHEMBL4517561	172121	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	70538373	174651	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	840	23	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C	nan
	CHEMBL4577691	174651	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	840	23	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C	nan
	154573825	175142	4	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4588946	175142	4	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	155561477	174346	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	811	22	12	11	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4570840	174346	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	811	22	12	11	-3.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155559104	173961	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4562270	173961	0	AGTRA	AT₁ receptor	Rat	7.4	pEC50	=	7.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155552475	173206	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4543860	173206	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155560024	174045	0	AGTRA	AT₁ receptor	Rat	4.4	pEC50	=	4.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	782	21	11	10	-1.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4564094	174045	0	AGTRA	AT₁ receptor	Rat	4.4	pEC50	=	4.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	782	21	11	10	-1.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	11943	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assayAgonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b00435
	145925549	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assayAgonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b00435
	CHEMBL4438122	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assayAgonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay	ChEMBL		None	None	None		None	10.1021/acs.jmedchem.8b00435
	11943	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	145925549	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4438122	3635	0	AGTR1	AT₁ receptor	Human	7.4	pEC50	=	7.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155542907	172332	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	CHEMBL4522038	172332	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	24	13	12	-1.5	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C	nan
	155541125	172121	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	CHEMBL4517561	172121	0	AGTR1	AT₁ receptor	Human	6.4	pEC50	=	6.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	904	27	12	11	-1.2	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(C)C)C(=O)O	nan
	155552475	173206	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4543860	173206	0	AGTRA	AT₁ receptor	Rat	6.4	pEC50	=	6.4	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	947	25	14	13	-2.5	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155561376	174828	0	AGTR1	AT₁ receptor	Human	5.4	pEC50	=	5.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	12	11	-1.4	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(N)=O	nan
	CHEMBL4581718	174828	0	AGTR1	AT₁ receptor	Human	5.4	pEC50	=	5.4	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	12	11	-1.4	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(N)=O	nan
	155560024	174045	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	782	21	11	10	-1.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4564094	174045	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	782	21	11	10	-1.4	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155553098	173264	0	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4545153	173264	0	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155553311	173287	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4546162	173287	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155540547	171679	0	AGTRA	AT₁ receptor	Rat	8.3	pEC50	=	8.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	13	-2.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(F)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4483576	171679	0	AGTRA	AT₁ receptor	Rat	8.3	pEC50	=	8.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	13	-2.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(F)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155548148	172870	0	AGTR1	AT₁ receptor	Human	7.3	pEC50	=	7.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	943	26	14	14	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4535997	172870	0	AGTR1	AT₁ receptor	Human	7.3	pEC50	=	7.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	943	26	14	14	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155551762	173164	0	AGTRA	AT₁ receptor	Rat	7.3	pEC50	=	7.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	26	13	12	-2.2	CCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4542709	173164	0	AGTRA	AT₁ receptor	Rat	7.3	pEC50	=	7.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	911	26	13	12	-2.2	CCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155546362	172706	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	26	12	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4532075	172706	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	26	12	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN1CCCC1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155553930	174594	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4576650	174594	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1177	26	13	12	-0.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	54726675	98672	0	AGTR1	AT₁ receptor	Bovine	6.3	pEC50	=	6.3	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	515	7	2	7	5.7	CCOc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	CHEMBL282566	98672	0	AGTR1	AT₁ receptor	Bovine	6.3	pEC50	=	6.3	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	515	7	2	7	5.7	CCOc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	155558003	173848	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4559421	173848	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1015	28	13	16	-2.1	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	86727577	115233	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at AT1 receptor (unknown origin)Agonist activity at AT1 receptor (unknown origin)	ChEMBL	422	2	1	5	3.6	C[C@H]1CN(C)CC[C@H]1c1cc2c(cc1-c1ccccc1F)OCC1=NNC(=O)[C@@H](C)N12	10.1021/jm5013006
	CHEMBL3355127	115233	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at AT1 receptor (unknown origin)Agonist activity at AT1 receptor (unknown origin)	ChEMBL	422	2	1	5	3.6	C[C@H]1CN(C)CC[C@H]1c1cc2c(cc1-c1ccccc1F)OCC1=NNC(=O)[C@@H](C)N12	10.1021/jm5013006
	155555310	173514	0	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	931	25	13	12	-2.2	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4551431	173514	0	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	931	25	13	12	-2.2	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155555310	173514	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	931	25	13	12	-2.2	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4551431	173514	0	AGTRA	AT₁ receptor	Rat	6.3	pEC50	=	6.3	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	931	25	13	12	-2.2	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	10533900	175122	2	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	CHEMBL4588454	175122	2	AGTR1	AT₁ receptor	Human	6.3	pEC50	=	6.3	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	90219582	115234	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at AT1 receptor (unknown origin)Agonist activity at AT1 receptor (unknown origin)	ChEMBL	436	2	1	5	3.9	Cc1ccc(-c2cc3c(cc2[C@@H]2CCN(C)C[C@@H]2C)N2C(=NNC(=O)[C@H]2C)CO3)c(F)c1	10.1021/jm5013006
	CHEMBL3355137	115234	0	AGTR1	AT₁ receptor	Human	5.3	pEC50	=	5.3	Binding	Agonist activity at AT1 receptor (unknown origin)Agonist activity at AT1 receptor (unknown origin)	ChEMBL	436	2	1	5	3.9	Cc1ccc(-c2cc3c(cc2[C@@H]2CCN(C)C[C@@H]2C)N2C(=NNC(=O)[C@H]2C)CO3)c(F)c1	10.1021/jm5013006
	24892627	55145	3	AGTR1	AT₁ receptor	Human	4.2	pEC50	=	4.2	Functional	PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]	ChEMBL	548	8	0	6	5.0	Cc1ccc2nc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)sc2c1	nan
	CHEMBL1460676	55145	3	AGTR1	AT₁ receptor	Human	4.2	pEC50	=	4.2	Functional	PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]	ChEMBL	548	8	0	6	5.0	Cc1ccc2nc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)sc2c1	nan
	CHEMBL1621632	55145	3	AGTR1	AT₁ receptor	Human	4.2	pEC50	=	4.2	Functional	PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]	ChEMBL	548	8	0	6	5.0	Cc1ccc2nc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)sc2c1	nan
	155558059	173838	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	CHEMBL4559239	173838	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	155552995	173266	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	27	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4545399	173266	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	27	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL938	207999	18	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	CHEMBL77838	207970	1	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(C)C)C(=O)O	nan
	CHEMBL312754	204624	13	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	154573825	175142	4	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4588946	175142	4	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	172198	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	2504	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	45266664	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	5272	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL408403	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	DB11842	400	40	AGTRA	AT₁ receptor	Rat	8.2	pEC50	=	8.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	54726672	98607	0	AGTR1	AT₁ receptor	Bovine	6.2	pEC50	=	6.2	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	517	6	2	7	6.0	CSc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	CHEMBL282082	98607	0	AGTR1	AT₁ receptor	Bovine	6.2	pEC50	=	6.2	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	517	6	2	7	6.0	CSc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	54726668	96556	0	AGTR1	AT₁ receptor	Bovine	5.2	pEC50	=	5.2	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	477	5	2	7	5.3	O=c1c(-c2ccccc2)c(O)c2sccc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)81134-3
	CHEMBL26875	96556	0	AGTR1	AT₁ receptor	Bovine	5.2	pEC50	=	5.2	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	477	5	2	7	5.3	O=c1c(-c2ccccc2)c(O)c2sccc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)81134-3
	155559827	174070	0	AGTR1	AT₁ receptor	Human	7.2	pEC50	=	7.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	970	27	13	14	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4564617	174070	0	AGTR1	AT₁ receptor	Human	7.2	pEC50	=	7.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	970	27	13	14	-2.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155539838	172051	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4515848	172051	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155547844	172853	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	942	26	14	13	-2.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4535678	172853	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	942	26	14	13	-2.2	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155553098	173264	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4545153	173264	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	155566196	174899	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4583284	174899	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	26	13	12	-1.3	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155567790	175205	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	877	24	13	12	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4590589	175205	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	877	24	13	12	-3.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155562469	174375	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	29	12	12	-1.1	C=CCOc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(=O)O)[C@@H](C)CC)cc1	nan
	CHEMBL4571382	174375	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	966	29	12	12	-1.1	C=CCOc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@H](C)C(=O)O)[C@@H](C)CC)cc1	nan
	155568289	175279	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	898	26	11	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4592000	175279	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	898	26	11	12	-1.0	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155560463	174195	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	CHEMBL4567667	174195	0	AGTRA	AT₁ receptor	Rat	7.2	pEC50	=	7.2	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1052	28	14	13	-0.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C	nan
	155553003	173230	0	AGTR1	AT₁ receptor	Human	7.2	pEC50	=	7.2	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	CHEMBL4544308	173230	0	AGTR1	AT₁ receptor	Human	7.2	pEC50	=	7.2	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	10533900	175122	2	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	CHEMBL4588454	175122	2	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	955	27	14	13	-2.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O	nan
	155544246	172521	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	887	24	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4527484	172521	0	AGTRA	AT₁ receptor	Rat	6.2	pEC50	=	6.2	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	887	24	12	11	-1.8	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155520024	172401	0	AGTR1	AT₁ receptor	Human	5.2	pEC50	=	5.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	27	13	12	-1.6	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4524570	172401	0	AGTR1	AT₁ receptor	Human	5.2	pEC50	=	5.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	959	27	13	12	-1.6	CN[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155558784	173931	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4561366	173931	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155543972	174170	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	13	12	-1.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4567103	174170	0	AGTR1	AT₁ receptor	Human	6.2	pEC50	=	6.2	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	917	28	13	12	-1.7	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL2392353	203929	4	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		None	nan
	155553098	173264	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL4545153	173264	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	969	28	16	13	-3.7	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C	nan
	CHEMBL938	207999	18	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C	nan
	155552886	173250	0	AGTR1	AT₁ receptor	Human	8.1	pEC50	=	8.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	13	-2.3	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4544902	173250	0	AGTR1	AT₁ receptor	Human	8.1	pEC50	=	8.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	13	-2.3	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155552886	173250	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	13	-2.3	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4544902	173250	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	13	13	-2.3	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)c(Cl)c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	1588251	58743	10	AGTR1	AT₁ receptor	Human	5.1	pEC50	=	5.1	Functional	PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]	ChEMBL	436	4	0	5	5.8	CCN1C(c2ccccc2)=C(c2ccccc2)S/C1=C\C=C1/SC(=S)N(C)C1=O	nan
	CHEMBL1704271	58743	10	AGTR1	AT₁ receptor	Human	5.1	pEC50	=	5.1	Functional	PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]	ChEMBL	436	4	0	5	5.8	CCN1C(c2ccccc2)=C(c2ccccc2)S/C1=C\C=C1/SC(=S)N(C)C1=O	nan
	145925550	174625	0	AGTR1	AT₁ receptor	Human	7.1	pEC50	=	7.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	903	24	13	12	-2.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4577270	174625	0	AGTR1	AT₁ receptor	Human	7.1	pEC50	=	7.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	903	24	13	12	-2.1	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	155540328	172057	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	CHEMBL4516066	172057	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	155559104	173961	0	AGTR1	AT₁ receptor	Human	7.1	pEC50	=	7.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	CHEMBL4562270	173961	0	AGTR1	AT₁ receptor	Human	7.1	pEC50	=	7.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	940	26	12	12	-1.6	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155540033	172046	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	CHEMBL4515768	172046	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	953	27	13	12	-1.9	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(C)C)C(N)=O	nan
	155541240	172172	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	928	26	12	11	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4518420	172172	0	AGTRA	AT₁ receptor	Rat	7.1	pEC50	=	7.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	928	26	12	11	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL2028943	202659	0	AGTR1	AT₁ receptor	Human	8.1	pEC50	=	8.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155539838	172051	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	CHEMBL4515848	172051	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	940	26	13	12	-1.5	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(=O)O	nan
	155552429	173311	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4546799	173311	0	AGTRA	AT₁ receptor	Rat	8.1	pEC50	=	8.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	155540328	172057	0	AGTR1	AT₁ receptor	Human	6.1	pEC50	=	6.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	CHEMBL4516066	172057	0	AGTR1	AT₁ receptor	Human	6.1	pEC50	=	6.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	1017	28	14	13	-1.6	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)C(N)=O	nan
	155563676	174498	0	AGTRA	AT₁ receptor	Rat	6.1	pEC50	=	6.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4574199	174498	0	AGTRA	AT₁ receptor	Rat	6.1	pEC50	=	6.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	961	26	14	13	-2.1	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	155559120	173941	0	AGTRA	AT₁ receptor	Rat	6.1	pEC50	=	6.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-1.8	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL4561769	173941	0	AGTRA	AT₁ receptor	Rat	6.1	pEC50	=	6.1	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	945	26	13	12	-1.8	CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O	nan
	CHEMBL2370909	203471	0	AGTR1	AT₁ receptor	Human	6.1	pEC50	=	6.1	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155552429	173311	0	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL4546799	173311	0	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	927	26	13	13	-2.9	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)[C@@H](C)OC)C(C)C	nan
	CHEMBL312754	204624	13	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O	nan
	155541440	172176	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	CHEMBL4518530	172176	0	AGTRA	AT₁ receptor	Rat	8.0	pEC50	=	8.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	954	28	13	12	-1.1	CCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(=O)O	nan
	172198	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	2504	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	45266664	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	5272	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL408403	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	DB11842	400	40	AGTR1	AT₁ receptor	Human	8.0	pEC50	=	8.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	54726674	99027	0	AGTR1	AT₁ receptor	Bovine	7.1	pEC50	=	7.1	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	505	6	2	7	5.9	CCc1cc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2s1	10.1016/S0960-894X(01)81134-3
	CHEMBL284877	99027	0	AGTR1	AT₁ receptor	Bovine	7.1	pEC50	=	7.1	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	505	6	2	7	5.9	CCc1cc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)c2s1	10.1016/S0960-894X(01)81134-3
	11944	3636	0	AGTRA	AT₁ receptor	Rat	6.0	pEC50	=	6.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	155552190	3636	0	AGTRA	AT₁ receptor	Rat	6.0	pEC50	=	6.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL4544228	3636	0	AGTRA	AT₁ receptor	Rat	6.0	pEC50	=	6.0	Binding	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL		None	None	None		None	nan
	CHEMBL2370909	203471	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL		None	None	None		CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)O	nan
	155558059	173838	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	CHEMBL4559239	173838	0	AGTR1	AT₁ receptor	Human	6.0	pEC50	=	6.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	790	23	12	11	-4.6	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O)C(C)C)C(C)C	nan
	155558784	173931	0	AGTRA	AT₁ receptor	Rat	6.0	pEC50	=	6.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	CHEMBL4561366	173931	0	AGTRA	AT₁ receptor	Rat	6.0	pEC50	=	6.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	756	9	7	8	1.3	CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC1=O	nan
	155569246	175335	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	869	25	13	12	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	CHEMBL4593310	175335	0	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Binding	Agonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 60 mins by luminescence based beta-arrestin recruitment assay	ChEMBL	869	25	13	12	-3.2	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(N)=O)C(C)C	nan
	54726673	98523	0	AGTR1	AT₁ receptor	Bovine	5.0	pEC50	=	5.0	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	477	6	2	5	5.8	COc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	CHEMBL28160	98523	0	AGTR1	AT₁ receptor	Bovine	5.0	pEC50	=	5.0	Binding	Inhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortexInhibition of [125I]AII binding to angiotensin II receptor of bovine adrenal cortex	ChEMBL	477	6	2	5	5.8	COc1ccc2c(O)c(-c3ccccc3)c(=O)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1	10.1016/S0960-894X(01)81134-3
	154573825	175142	4	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	CHEMBL4588946	175142	4	AGTR1	AT₁ receptor	Human	7.0	pEC50	=	7.0	Functional	Agonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at human AT1R expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	742	22	12	10	-2.4	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C)C(C)C	nan
	155553003	173230	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	CHEMBL4544308	173230	0	AGTRA	AT₁ receptor	Rat	7.0	pEC50	=	7.0	Functional	Agonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assayAgonist activity at rat AT1aR expressed in HEK293 cells incubated for 30 mins by IP1 accumulation assay	ChEMBL	791	23	12	11	-4.0	CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)C(C)C)C(C)C	nan
	10032858	29358	0	AGTR1	AT₁ receptor	Rabbit	10.4	pIC50	=	10.4	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	729	12	2	9	7.1	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2occ(Cl)c2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL138690	29358	0	AGTR1	AT₁ receptor	Rabbit	10.4	pIC50	=	10.4	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	729	12	2	9	7.1	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2occ(Cl)c2Cl)cc1	10.1007/s00044-013-0831-x
	10032858	29358	0	AGTR1	AT₁ receptor	Rabbit	10.4	pIC50	=	10.4	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	729	12	2	9	7.1	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2occ(Cl)c2Cl)cc1	10.1021/jm00052a006
	CHEMBL138690	29358	0	AGTR1	AT₁ receptor	Rabbit	10.4	pIC50	=	10.4	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	729	12	2	9	7.1	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2occ(Cl)c2Cl)cc1	10.1021/jm00052a006
	9895212	118884	0	AGTR1	AT₁ receptor	Human	10.3	pIC50	=	10.3	Binding	Inhibition of Angiotensin II receptor, type 1Inhibition of Angiotensin II receptor, type 1	ChEMBL	614	9	1	6	7.0	CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)C(c2ccccc2)c2ccccc2)cc1	10.1021/jm9504722
	CHEMBL346728	118884	0	AGTR1	AT₁ receptor	Human	10.3	pIC50	=	10.3	Binding	Inhibition of Angiotensin II receptor, type 1Inhibition of Angiotensin II receptor, type 1	ChEMBL	614	9	1	6	7.0	CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)C(c2ccccc2)c2ccccc2)cc1	10.1021/jm9504722
	10417251	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL265797	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10417251	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	In vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaIn vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1016/S0960-894X(01)80595-3
	CHEMBL265797	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	In vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaIn vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1016/S0960-894X(01)80595-3
	10417251	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL265797	96217	0	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	691	11	2	8	6.5	CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	3025727	183204	6	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Functional	Antagonist activity at angiotensin AT1 receptor in rabbit aortic strip assessed as inhibition of angiotensin 2-induced contractile responseAntagonist activity at angiotensin AT1 receptor in rabbit aortic strip assessed as inhibition of angiotensin 2-induced contractile response	ChEMBL	452	8	2	6	5.0	CCCCc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/j.bmc.2010.10.043
	CHEMBL48242	183204	6	AGTR1	AT₁ receptor	Rabbit	10.3	pIC50	=	10.3	Functional	Antagonist activity at angiotensin AT1 receptor in rabbit aortic strip assessed as inhibition of angiotensin 2-induced contractile responseAntagonist activity at angiotensin AT1 receptor in rabbit aortic strip assessed as inhibition of angiotensin 2-induced contractile response	ChEMBL	452	8	2	6	5.0	CCCCc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/j.bmc.2010.10.043
	10349732	118003	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	695	13	2	9	7.1	CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3)c2=O)c1	10.1007/s00044-013-0831-x
	CHEMBL341828	118003	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	695	13	2	9	7.1	CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3)c2=O)c1	10.1007/s00044-013-0831-x
	10032820	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	CHEMBL339672	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	10032820	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1021/jm00019a004
	CHEMBL339672	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1021/jm00019a004
	10349732	118003	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	695	13	2	9	7.1	CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3)c2=O)c1	10.1021/jm00052a006
	CHEMBL341828	118003	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	695	13	2	9	7.1	CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3)c2=O)c1	10.1021/jm00052a006
	10032820	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	CHEMBL339672	116556	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	7.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	10439848	118460	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	717	12	2	8	6.9	CCCCc1nn(-c2cc(NC(=O)C3CC3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL343309	118460	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	717	12	2	8	6.9	CCCCc1nn(-c2cc(NC(=O)C3CC3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10439848	118460	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	717	12	2	8	6.9	CCCCc1nn(-c2cc(NC(=O)C3CC3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL343309	118460	0	AGTR1	AT₁ receptor	Rabbit	10.1	pIC50	=	10.1	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	717	12	2	8	6.9	CCCCc1nn(-c2cc(NC(=O)C3CC3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	10010071	116601	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	CHEMBL339722	116601	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	9829012	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSABinding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSA	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm00073a024
	CHEMBL24322	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSABinding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSA	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm00073a024
	44311455	102032	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	782	17	1	9	8.2	CCCc1nc(CC)c(C(=O)OCCN(C(=O)c2ccccc2)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL305017	102032	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	782	17	1	9	8.2	CCCc1nc(CC)c(C(=O)OCCN(C(=O)c2ccccc2)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311580	102067	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	706	16	2	9	6.9	CCCc1nc(CC)c(C(=O)OCCC(=O)Nc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL305238	102067	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	706	16	2	9	6.9	CCCc1nc(CC)c(C(=O)OCCC(=O)Nc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311676	102348	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	706	17	2	9	7.0	CCCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OCCC(=O)Nc2ccccc2)c(F)c1	10.1016/S0960-894X(00)80077-3
	CHEMBL307318	102348	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	706	17	2	9	7.0	CCCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OCCC(=O)Nc2ccccc2)c(F)c1	10.1016/S0960-894X(00)80077-3
	44311435	197595	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	693	17	1	9	7.3	CCCc1nc(CC)c(C(=O)OCCCOc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL69721	197595	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	693	17	1	9	7.3	CCCc1nc(CC)c(C(=O)OCCCOc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311415	197657	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	705	17	1	9	7.5	CCCc1nc(CC)c(C(=O)OCCCC(=O)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL70161	197657	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	705	17	1	9	7.5	CCCc1nc(CC)c(C(=O)OCCCC(=O)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311434	197695	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	707	18	1	9	7.5	CCCc1nc(CC)c(C(=O)OCCCOCc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL70370	197695	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	707	18	1	9	7.5	CCCc1nc(CC)c(C(=O)OCCCOCc2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311072	197756	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	679	15	1	9	7.1	CCCc1nc(CC)c(C(=O)OCc2ccccc2OC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL70789	197756	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	679	15	1	9	7.1	CCCc1nc(CC)c(C(=O)OCc2ccccc2OC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311073	197770	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	746	16	1	10	6.6	CCCc1nc(CC)c(C(=O)OCCCN2C(=O)c3ccccc3C2=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL70843	197770	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	746	16	1	10	6.6	CCCc1nc(CC)c(C(=O)OCCCN2C(=O)c3ccccc3C2=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	44311414	197793	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	677	15	1	9	6.8	CCCc1nc(CC)c(C(=O)OCC(=O)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	CHEMBL70935	197793	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Binding affinity for Angiotensin II receptor, type 1Binding affinity for Angiotensin II receptor, type 1	ChEMBL	677	15	1	9	6.8	CCCc1nc(CC)c(C(=O)OCC(=O)c2ccccc2)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F	10.1016/S0960-894X(00)80077-3
	9829012	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneDisplacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membrane	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)80517-5
	CHEMBL24322	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneDisplacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membrane	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(01)80517-5
	73347893	91954	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysisDisplacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysis	ChEMBL	531	10	2	4	7.3	CCCc1nc2c(C)cc(NC(=O)CCc3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1	10.1016/j.ejmech.2013.08.014
	CHEMBL2435828	91954	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysisDisplacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysis	ChEMBL	531	10	2	4	7.3	CCCc1nc2c(C)cc(NC(=O)CCc3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1	10.1016/j.ejmech.2013.08.014
	9829012	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Displacement of [125I]Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aortaDisplacement of [125I]Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aorta	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(00)80335-2
	CHEMBL24322	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Displacement of [125I]Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aortaDisplacement of [125I]Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aorta	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1016/S0960-894X(00)80335-2
	19754061	102022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	657	15	2	7	7.7	CCCCC(=O)Nc1cc2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)CCC4CCCC4)cc3)c2nc1C	10.1016/S0960-894X(01)81115-X
	CHEMBL304947	102022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	657	15	2	7	7.7	CCCCC(=O)Nc1cc2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)CCC4CCCC4)cc3)c2nc1C	10.1016/S0960-894X(01)81115-X
	44309719	197427	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	544	9	1	6	6.1	CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCC2CCCC2)cc1	10.1016/S0960-894X(01)81115-X
	CHEMBL68638	197427	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	544	9	1	6	6.1	CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCC2CCCC2)cc1	10.1016/S0960-894X(01)81115-X
	10010071	116601	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	CHEMBL339722	116601	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	9829012	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Inhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aortaInhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aorta	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm9504722
	CHEMBL24322	91884	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10	Binding	Inhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aortaInhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aorta	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm9504722
	9829012	91884	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Inhibitory concentration against angiotensin II receptor, type 1Inhibitory concentration against angiotensin II receptor, type 1	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm058225d
	CHEMBL24322	91884	0	AGTR1	AT₁ receptor	Human	10.0	pIC50	=	10	Binding	Inhibitory concentration against angiotensin II receptor, type 1Inhibitory concentration against angiotensin II receptor, type 1	ChEMBL	550	9	2	7	5.5	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1	10.1021/jm058225d
	9809961	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL316300	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10439862	118022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	719	13	2	8	7.3	CCCCc1nn(-c2cc(NC(=O)CCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL341934	118022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	719	13	2	8	7.3	CCCCc1nn(-c2cc(NC(=O)CCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10010195	118434	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	733	13	2	8	7.5	CCCCc1nn(-c2cc(NC(=O)CC(C)C)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL343142	118434	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	733	13	2	8	7.5	CCCCc1nn(-c2cc(NC(=O)CC(C)C)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	9809961	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaIn vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1016/S0960-894X(01)80595-3
	CHEMBL316300	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaIn vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1016/S0960-894X(01)80595-3
	9917295	102246	7	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	633	15	2	8	7.1	CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3cc(NC(=O)CCCC)c(C)nc32)cc1	10.1016/S0960-894X(01)81115-X
	CHEMBL306407	102246	7	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	633	15	2	8	7.1	CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3cc(NC(=O)CCCC)c(C)nc32)cc1	10.1016/S0960-894X(01)81115-X
	9809961	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIIn vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00043a020
	CHEMBL316300	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIIn vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00043a020
	9809961	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL316300	106439	2	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	668	10	1	7	6.9	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	10439862	118022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	719	13	2	8	7.3	CCCCc1nn(-c2cc(NC(=O)CCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL341934	118022	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	719	13	2	8	7.3	CCCCc1nn(-c2cc(NC(=O)CCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	10010195	118434	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	733	13	2	8	7.5	CCCCc1nn(-c2cc(NC(=O)CC(C)C)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL343142	118434	0	AGTR1	AT₁ receptor	Rabbit	10.0	pIC50	=	10.0	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	733	13	2	8	7.5	CCCCc1nn(-c2cc(NC(=O)CC(C)C)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	10395394	31472	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	767	13	2	8	7.7	CCCCc1nn(-c2cc(NC(=O)Cc3ccccc3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL140708	31472	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	767	13	2	8	7.7	CCCCc1nn(-c2cc(NC(=O)Cc3ccccc3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10032851	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	CHEMBL124771	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	9809637	197425	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	643	15	2	7	7.4	CCCCC(=O)Nc1cnc2c(c1)nc(CCCC)n2Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCC2CCCC2)cc1	10.1016/S0960-894X(01)81115-X
	CHEMBL68618	197425	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranesIn vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membranes	ChEMBL	643	15	2	7	7.4	CCCCC(=O)Nc1cnc2c(c1)nc(CCCC)n2Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCC2CCCC2)cc1	10.1016/S0960-894X(01)81115-X
	10032851	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	CHEMBL124771	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	10395394	31472	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	767	13	2	8	7.7	CCCCc1nn(-c2cc(NC(=O)Cc3ccccc3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	CHEMBL140708	31472	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparationTested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a rabbit aorta AT1 receptor preparation	ChEMBL	767	13	2	8	7.7	CCCCc1nn(-c2cc(NC(=O)Cc3ccccc3)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1021/jm00052a006
	44210588	119581	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneTested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane	ChEMBL	633	12	3	8	5.8	CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NC(C)C)cc3c2=O)cc1	10.1016/S0960-894X(01)81126-4
	CHEMBL353037	119581	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneTested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane	ChEMBL	633	12	3	8	5.8	CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NC(C)C)cc3c2=O)cc1	10.1016/S0960-894X(01)81126-4
	10032851	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	CHEMBL124771	16470	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	729	11	2	9	6.6	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	10327309	113152	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	691	12	2	9	6.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1F	10.1007/s00044-011-9815-x
	CHEMBL332576	113152	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	691	12	2	9	6.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1F	10.1007/s00044-011-9815-x
	10395335	116336	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	757	12	2	8	7.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	CHEMBL339256	116336	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	757	12	2	8	7.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1007/s00044-011-9815-x
	10372451	116546	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	685	11	2	9	6.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	CHEMBL339605	116546	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	685	11	2	9	6.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	10327309	113152	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	691	12	2	9	6.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1F	10.1021/jm00019a004
	CHEMBL332576	113152	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	691	12	2	9	6.0	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1F	10.1021/jm00019a004
	10395335	116336	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	757	12	2	8	7.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1021/jm00019a004
	CHEMBL339256	116336	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	757	12	2	8	7.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F	10.1021/jm00019a004
	10372451	116546	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	685	11	2	9	6.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	CHEMBL339605	116546	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	685	11	2	9	6.4	CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	10372093	112026	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIIn vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII	ChEMBL	652	10	1	7	6.4	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2F)cc1	10.1021/jm00043a020
	CHEMBL330533	112026	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIIn vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII	ChEMBL	652	10	1	7	6.4	CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2F)cc1	10.1021/jm00043a020
	44314822	102237	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membraneIn vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membrane	ChEMBL	691	13	2	8	6.7	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC2CC2)cc1F	10.1016/0960-894X(94)85036-4
	CHEMBL306362	102237	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membraneIn vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membrane	ChEMBL	691	13	2	8	6.7	CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC2CC2)cc1F	10.1016/0960-894X(94)85036-4
	10259411	30251	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	734	13	3	8	7.0	CCCCc1nn(-c2cc(NC(=O)NCCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	CHEMBL139452	30251	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	734	13	3	8	7.0	CCCCc1nn(-c2cc(NC(=O)NCCC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1	10.1007/s00044-013-0831-x
	10485116	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1007/s00044-013-0831-x
	CHEMBL338101	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at AT1 receptor in rabbit aorta membranesAntagonist activity at AT1 receptor in rabbit aorta membranes	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1007/s00044-013-0831-x
	10462598	113397	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	6.7	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1F	10.1007/s00044-011-9815-x
	CHEMBL332909	113397	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	723	12	2	8	6.7	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1F	10.1007/s00044-011-9815-x
	10485116	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1007/s00044-011-9815-x
	CHEMBL338101	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1007/s00044-011-9815-x
	10395076	167738	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	CHEMBL435811	167738	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorAntagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1007/s00044-011-9815-x
	10462598	113397	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	723	12	2	8	6.7	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1F	10.1021/jm00019a004
	CHEMBL332909	113397	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	723	12	2	8	6.7	CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1F	10.1021/jm00019a004
	10485116	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1021/jm00019a004
	CHEMBL338101	116108	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	733	14	2	8	7.0	CCCCNC(=O)c1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)c4ccccc4Cl)cc3)c2=O)c1	10.1021/jm00019a004
	10395076	167738	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	CHEMBL435811	167738	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	10395076	167738	0	AGTR1	AT₁ receptor	Human	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	CHEMBL435811	167738	0	AGTR1	AT₁ receptor	Human	9.9	pIC50	=	9.9	Binding	In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.	ChEMBL	715	13	2	10	6.1	CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1F	10.1021/jm00019a004
	10259411	30251	0	AGTR1	AT₁ receptor	Rabbit	9.9	pIC50	=	9.9	Binding

Join us

Cite us

Main reference

Ligand source activities (1 row/activity)