CHEMBL5275873


SMILES Cc1ccc(CC(=O)N2CCC(O)(c3cccc(O)c3)C(CN(C)C)C2)cc1
InChIKey JPGJTWGGJSUXMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.82 8.82 8.82 ChEMBL
δ OPRD Human Opioid A pKi 6.93 6.93 6.93 ChEMBL
κ OPRK Human Opioid A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.32 8.32 8.32 ChEMBL
μ OPRM Human Opioid A pEC50 8.25 8.25 8.25 ChEMBL