Pathway preferred ligand counts

This page shows the number of ligands with a pathway preference.

Class
(Family)		 A (Rhodopsin) B1 (Secretin) B2 (Adhesion) C (Glutamate) F (Frizzled) T2 (Taste 2)
Total
No. biased ligands 1,576 86 0 10 0 0
No. GPCRs with ligand 240 15 0 13 0 0


Pathway preference ligand coverage by GPCR class


Classes: 
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Receptor names:


Primary transducer count0214CASRGLRGLP1RCALRLCALCRLSHRCXCR4CXCR3CXCR2CXCR1CCR5CCR2CCR10CCR1V2RV1BRV1AROXYRRXFP1PAR2OPRXOPRMOPRKOPRDNPY1RNPSR1MSHRMC5RMC4RMC3RGHSRGALR2FPR2FPR1EDNRAAPJAGTR1AA3RAA2BRAA1RPE2R4PE2R2S1PR1LPAR1FFAR1CNR2CNR1HRH4HRH3DRD5DRD2DRD1ADRB2ADRB1ADA2CADA1AACM5ACM4ACM3ACM2ACM15HT7R5HT2C5HT2B5HT2A5HT1B5HT1AArrestinErkG12/13Gi/oGq/11Gs
Receptor names:

Inner circle colors indicate a number of ligands:
< 10
< 20
< 30
30+

Transducers
○ Gαs ○ Gαi/o ○ Gαq/11 ○ Gα12/13 ○ β-Arrestin
Primary transducer frequency (from low to high)



Class A
(Rhodopsin)




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)