The main article A community Biased signaling Atlas has been published on Nature Chemical Biology.
We invite you all to read the article to have a deeper insight of this new resource.


Biased Signaling Atlas

The Biased Signaling Atlas offers:

Biased signaling entails hormones, probes, or drugs binding the same GPCR but engaging different intracellular signaling pathways leading to distinct functional outcomes. This may let drugs favor therapeutic over adverse signal pathways.


  • Biased ligands
  • 132 Physiology-biased
  • 132 Pathway-biased
  • 8,616 Total datapoints
  • Pathways
  • 324 Pathway effects
  • Pathway-preferring ligands
  • 1,672 Ligands
  • Reference ligands
  • 94 For pathway-bias
  • 783 For physiology-bias


The Biased Signaling Atlas is a new community platform.
Read the article, try it out and let us know what you think.

Related resources

GPCRdb, GproteinDb, ArrestinDb and Biased Signaling Atlas cover related aspects of signal transduction while serving dedicated research communities and use cases.