Biased Signaling Atlas

Ligand	Amino Acid	Generic Number	Segment	Interaction Type


2MeSADP	R93	3.21x21	TM3	polar (charge-charge)
2MeSADP	R93	3.21x21	TM3	polar (hydrogen bond)
2MeSADP	C97	3.25x25	TM3	polar (hydrogen bond with backbone)
2MeSADP	S101	3.29x29	TM3	Van der Waals
2MeSADP	V102	3.30x30	TM3	Van der Waals
2MeSADP	Y105	3.33x33	TM3	aromatic (face-to-face)
2MeSADP	Y105	3.33x33	TM3	polar (hydrogen bond)
2MeSADP	F106	3.34x34	TM3	hydrophobic
2MeSADP	Y109	3.37x37	TM3	Van der Waals
2MeSADP	M152	4.53x53	TM4	Van der Waals
2MeSADP	L155	4.56x56	TM4	hydrophobic
2MeSADP	S156	4.57x57	TM4	Van der Waals
2MeSADP	N159	4.60x60	TM4	Van der Waals
2MeSADP	T163	4.64x64	TM4	Van der Waals
2MeSADP	K174		ECL2	Van der Waals
2MeSADP	C175	45.50x50	ECL2	polar (hydrogen bond with backbone)
2MeSADP	K179		ECL2	polar (hydrogen bond)
2MeSADP	H187	5.36x36	TM5	polar (hydrogen bond)
2MeSADP	V190	5.39x39	TM5	hydrophobic
2MeSADP	N191	5.40x40	TM5	polar (hydrogen bond)
2MeSADP	C194	5.43x43	TM5	Van der Waals
2MeSADP	R256	6.55x55	TM6	polar (charge-charge)
2MeSADP	R256	6.55x55	TM6	polar (hydrogen bond)
2MeSADP	Y259	6.58x58	TM6	polar (hydrogen bond)
2MeSADP	Q263	6.62x62	TM6	polar (hydrogen bond)
2MeSADP	F277	7.32x31	TM7	Van der Waals
2MeSADP	K280	7.35x34	TM7	polar (charge-charge)
2MeSADP	K280	7.35x34	TM7	polar (hydrogen bond)