PDB
6I9K
Resolution
2.2 Å
Released
July 3, 2019
Receptor
Rhodopsin
Class
A
Species
Hasarius adansoni
Ligand
all-trans-retinal
Function
Inverse agonist
Reference
10.1073/PNAS.1902192116

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Ligand Amino Acid Generic Number Segment Interaction Type
all-trans-retinal Y126 3.28x28 TM3 hydrophobic
all-trans-retinal I202 45.52x52 ECL2 hydrophobic
all-trans-retinal Y218 5.42x43 TM5 hydrophobic
all-trans-retinal V222 5.46x461 TM5 hydrophobic
all-trans-retinal Y223 5.47x47 TM5 hydrophobic
all-trans-retinal W286 6.44x44 TM6 hydrophobic
all-trans-retinal W290 6.48x48 TM6 hydrophobic
all-trans-retinal Y293 6.51x51 TM6 hydrophobic
all-trans-retinal L294 6.52x52 TM6 hydrophobic
all-trans-retinal A317 7.39x38 TM7 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 K N L R ICL1ECL1 T W V I ECL1ICL2 G M A G K P L ICL2ECL2 G W S R Y V P E G S M T S C T I D Y I D T ECL2ICL3 I K S L R S ICL3ECL3 D R T W L ECL3N-term M L P H A A K M A A R V A G D H D G R N I S I V D L L P E D M L P M I H E H W Y K F P P M N-termC-term P C L K C G S D S P K G D S A S T V A E S E K A G E C-term E T S M H Y I L G M L I I V I G I I S V S G N G V V M Y L M M T V T P G N F L V L N L A L S D F G M L F F M M P T M S I N C F A E G P F M C E L Y G M I G S L F G S A S I W S L V M I T L D R Y N V I V K T K V G A L L R M L F V W I W S L G W T I A P M Y A I N P M S Y L I A Y A I F V Y F V P L F I I I Y C Y A F I V M Q V A A H E K S L R E Q A K K M N N E D N K K A S A E F R L A K V A F M T I C C W F M A W T P Y L T L S F L G I F S T P M T S V W G A I F A K A S A C Y N P I V Y G I S H P K L H D Y R A A K F
Helix box plot — Download: PNG | SVG G N G S V S I I G I V I I L M G L I Y H 1 L N L A L S D F G M L F F M M P T M S I 2 M V L S W I S A S G F L S G I M G Y L E 3 A L L R M L F V W I W S L G W T I A P M 4 Y C Y I I I F L P V F Y V F I A Y A I L Y 5 F M T I C C W F M A W T P Y L T L S F L 6 I P N Y C A S A K A F I A G W V S T M 7

GPCRdb(A)
GPCRdb(A)
Rhodopsin
TM3
3x28 3.28x28 Y126
ECL2
45x52 45.52x52 I202
TM5
5x43 5.42x43 Y218
5x461 5.46x461 V222
5x47 5.47x47 Y223
TM6
6x44 6.44x44 W286
6x48 6.48x48 W290
6x51 6.51x51 Y293
6x52 6.52x52 L294
TM7
7x38 7.39x38 A317