PDB
7D76
Resolution
3.1 Å
Released
Feb. 3, 2021
Receptor
ADGRG3
Class
B2
Species
Homo sapiens
Ligand
Function
beclomethasone
Agonist
Reference
10.1038/S41586-020-03083-W

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
beclomethasone S272 1.43x43 TM1 Van der Waals
beclomethasone F323 2.64x64 TM2 hydrophobic
beclomethasone F345 3.36x36 TM3 hydrophobic
beclomethasone L349 3.40x40 TM3 Van der Waals
beclomethasone W421 45.51x51 ECL2 Van der Waals
beclomethasone W490 6.53x53 TM6 Van der Waals
beclomethasone A493 6.56x56 TM6 Van der Waals
beclomethasone I494 6.57x57 TM6 Van der Waals
beclomethasone T496 ECL3 Van der Waals
beclomethasone L498 ECL3 hydrophobic
beclomethasone F506 7.42x41 TM7 hydrophobic
beclomethasone N510 7.46x45 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 E R F K S ICL1ECL1 G S K G ECL1ICL2 V F N T Y F G ICL2ECL2 S Y G L Y T I R D R E N R T S L E L C W F R E G T T M ECL2ICL3 A V K E R G ICL3ECL3 T P L G L S ECL3N-term M A T P R G L G A L L L L L L L P T S G Q E K P T E G P R N T C L G S N N M Y D N-termC-term L P S Q S T T V S S S T A R L D Q A H S A S Q E C-term D Q S T V H I L T R I S Q A G C G V S M I F L A F T I I L Y A F L R L S R E D A P K I H V A L G G S L F L L N L A F L V N V G S S D A A C W A R G A V F H Y F L L C A F T W M G L E A F H L Y L L A V R H Y F L K L S L V G W G L P A L M V I G T G S A N Y A L Y I T V H G Y F L I T F L F G M V V L A L V V W K I F T L S R A T K N R K K V L T L L G L S S L V G V T W G L A I F T V Y I F A L F N S L Q G V F I C C W F T I L Y
Helix box plot — Download: PNG | SVG A L F I M S V G C G A Q S I R T L I H V 1 V A L G G S L F L L N L A F L V N V G S 2 L G M W T F A C L L F Y H F V A G R A W 3 Y F L K L S L G V W G L P A L M V I G T G 4 L V V M G F L F T I L F Y G H V T I Y L A 5 L G L S S L V G V T W G L A I F 6 C C I F V G Q L S N F L A F I Y V T 7

GPCRdb(A)
GPCRdb(B)
ADGRG3
TM1
1x39 1.43x43 S272
TM2
2x57 2.64x64 F323
TM3
3x32 3.36x36 F345
3x36 3.40x40 L349
ECL2
45x51 45.51x51 W421
TM6
6x48 6.53x53 W490
6x51 6.56x56 A493
6x52 6.57x57 I494
TM7
7x37 7.42x41 F506
7x41 7.46x45 N510