PDB
7T6V
Resolution
3.1 Å
Released
March 30, 2022
Receptor
FPR2/ALX
Class
A
Species
Homo sapiens
Ligand
fMLFII
Function
Agonist
Reference
10.1038/S41467-022-28586-0

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
fMLFII V105 3.32x32 TM3 hydrophobic
fMLFII D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
fMLFII L109 3.36x36 TM3 Van der Waals
fMLFII L109 3.36x36 TM3 hydrophobic
fMLFII F110 3.37x37 TM3 Van der Waals
fMLFII F110 3.37x37 TM3 hydrophobic
fMLFII C176 45.50x50 ECL2 Van der Waals
fMLFII F178 45.52x52 ECL2 hydrophobic
fMLFII F178 45.52x52 ECL2 Van der Waals
fMLFII R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
fMLFII R205 5.42x43 TM5 polar (charge-assisted hydrogen bond)
fMLFII W254 6.48x48 TM6 Van der Waals
fMLFII F257 6.51x51 TM6 Van der Waals
fMLFII V284 7.35x34 TM7 Van der Waals
fMLFII V284 7.35x34 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 T R ICL1ECL1 E K W P F ECL1ICL2 P V W A Q N H R ICL2ECL2 T T V T I P N G D T Y C T F N F A S W G G ECL2ICL3 M I K S ICL3ECL3 L K E M L F Y G K ECL3N-term M E T N F S T P L N E Y E E V S Y E N-termC-term P T S L E R A L S E D S A P T N D T A A N S A S P P A E T E L Q A M C-term S A G Y T V L R I L P L V V L G V T F V L G V L G N G L V I W V A G F R M T V T T I C Y L N L A L A D F S F T A T L P F L I V S M A M G G W F L C K L I H I V V D I N L F G S V F L I G F I A L D R C I C V L H T V S L A M K V I V G P W I L A L V L T L P V F L F L T P E E R L K V A I T M L T A R G I I R F V I G F S L P M S I V A I C Y G L I A A K I H K K G S R P L R V L T A V V A S F F I C W F P F Q L V A L L G T V W Y K I I D I L V N P T S S L A F F N S C L N P M L Y V F V G Q D L I H F R E R S L
Helix box plot — Download: PNG | SVG G N G L V G L V F T V G L V V L P L I R 1 L N L A L A D F S F T A T L P F L I V S 2 F G I L F V S G F L N I D V V I H I L K 3 A M K V I V G P W I L A L V L T L P V 4 Y C I A V I S M P L S F G I V F R I I G R 5 T A V V A S F F I C W F P F Q L V A L L 6 M P N L C S N F F A L S S T P N V L I 7

GPCRdb(A)
GPCRdb(A)
FPR2/ALX
TM3
3x32 3.32x32 V105
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
ECL2
45x50 45.50x50 C176
45x52 45.52x52 F178
TM5
5x39 5.38x39 R201
5x43 5.42x43 R205
TM6
6x48 6.48x48 W254
6x51 6.51x51 F257
TM7
7x34 7.35x34 V284