PDB
7VVN
Resolution
3.8 Å
Released
Aug. 3, 2022
Receptor
PTH1
Class
B1
Species
Homo sapiens
Ligand
PTH
Function
Agonist
Reference
10.1016/J.MOLCEL.2022.07.003

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
PTH F184 1.36x36 TM1 hydrophobic
PTH Q364 5.40x40 TM5 polar (hydrogen bond)
PTH I367 5.43x43 TM5 hydrophobic
PTH I367 5.43x43 TM5 Van der Waals
PTH L368 5.44x44 TM5 hydrophobic
PTH L368 5.44x44 TM5 Van der Waals
PTH F424 6.56x56 TM6 Van der Waals
PTH F424 6.56x56 TM6 polar (hydrogen bond with backbone)
PTH M425 6.57x57 TM6 polar (hydrogen bond with backbone)
PTH M425 6.57x57 TM6 Van der Waals
PTH T427 ECL3 polar (hydrogen bond with backbone)
PTH T427 ECL3 Van der Waals
PTH T430 ECL3 Van der Waals
PTH E444 7.42x41 TM7 polar (charge-assisted hydrogen bond)
PTH M445 7.43x42 TM7 Van der Waals

PTH

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R R L H ICL1ECL1 L D E A E R L T E E E L R A I A Q A P P P P A T A A A ECL1ICL2 A F F ICL2ECL2 N T G C W D L S S ECL2ICL3 R E T N A G R C ICL3ECL3 P Y T E V S ECL3N-term M G T A R I A P G L A L L L C C P V L S S A Y A L V D A D D V M T K E E Q I F L L H R A Q A Q C E K R L K E V L Q R P A S I M E S D K G W T S A S T S G K P R K D K A S G K L Y P E S E E D K E A P T G S R Y R G R P C L P E W D H I L C W P L G A P G E V V A V P C P D Y I Y D F N H K G H A Y R R C D R N G S W E L V P G H N R T W A N Y S E C V K N-termC-term S G S S S Y S Y G P M V S H T S V T N V G P R V G L G L P L S P R L L P T A T T N G H P Q L P G H A K P G T P A L E T L E T T P P A M A A P K D D G F L N G S C S G L D E E A S G P E R P P A L L Q E E W E T V M C-term F L T N E T R E R E V F D R L G M I Y T V G Y S V S L A S L T V A V L I L A Y F C T R N Y I H M H L F L S F M L R A V S I F V K D A V L Y S G A T G Y A G C R V A V T F F L Y F L A T N Y Y W I L V E G L Y L H S L I F M S E K K Y L W G F T V F G W G L P A V F V A V W V S V R A T L A G N K K W I I Q V P I L A S I V L N F I L F I N I V R V L A T K L D T R Q Q Y R K L L K S T L V L M P L F G V H Y I V F M A T G T L W Q V Q M H Y E M L F N S F Q G F F V A I I Y C F C N G E I K K W T L K R K V Q A E S W S R A L D F A R
Helix box plot — Download: PNG | SVG T L S A L S V S Y G V T Y I M G L R D F 1 M H L F L S F M L R A V S I F V K D A V 2 V L I W Y Y N T A L F Y L F F T V A V R 3 Y L W G F T V G F W G L P A V F V A V W V 4 F L I F N L V I S A L I P V Q I I W K K N 5 L V L M P L F G V H Y I V F M A T 6 I A V F F G Q F S N F L M E Y H M Q V 7

GPCRdb(A)
GPCRdb(B)
PTH1 receptor
TM1
1x32 1.36x36 F184
TM5
5x44 5.40x40 Q364
5x47 5.43x43 I367
5x48 5.44x44 L368
TM6
6x51 6.56x56 F424
6x52 6.57x57 M425
TM7
7x37 7.42x41 E444
7x38 7.43x42 M445