Structure information

Y4 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7X9C

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

PUBLICATION DATE

May 18, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Pancreatic polypeptide C94 2.57x56 TM2 polar (hydrogen bond)
Pancreatic polypeptide T98 2.61x60 TM2 Van der Waals
Pancreatic polypeptide Y101 2.64x63 TM2 Van der Waals
Pancreatic polypeptide Y101 2.64x63 TM2 polar (hydrogen bond with backbone)
Pancreatic polypeptide Y101 2.64x63 TM2 polar (hydrogen bond)
Pancreatic polypeptide T102 2.65x64 TM2 Van der Waals
Pancreatic polypeptide D105 ECL1 polar (charge-assisted hydrogen bond)
Pancreatic polypeptide Q121 3.32x32 TM3 polar (hydrogen bond)
Pancreatic polypeptide Q121 3.32x32 TM3 Van der Waals
Pancreatic polypeptide V125 3.36x36 TM3 Van der Waals
Pancreatic polypeptide F174 4.60x61 TM4 Van der Waals
Pancreatic polypeptide F174 4.60x61 TM4 hydrophobic
Pancreatic polypeptide F184 ECL2 Van der Waals
Pancreatic polypeptide F184 ECL2 hydrophobic
Pancreatic polypeptide H185 ECL2 Van der Waals
Pancreatic polypeptide N187 ECL2 Van der Waals
Pancreatic polypeptide H188 ECL2 polar (hydrogen bond)
Pancreatic polypeptide H188 ECL2 Van der Waals
Pancreatic polypeptide S189 ECL2 Van der Waals
Pancreatic polypeptide K190 ECL2 Van der Waals
Pancreatic polypeptide L192 ECL2 Van der Waals
Pancreatic polypeptide L192 ECL2 hydrophobic
Pancreatic polypeptide T202 45.51x51 ECL2 Van der Waals
Pancreatic polypeptide R211 5.35x36 TM5 Van der Waals
Pancreatic polypeptide T215 5.39x40 TM5 polar (hydrogen bond)
Pancreatic polypeptide T215 5.39x40 TM5 Van der Waals
Pancreatic polypeptide L218 5.42x43 TM5 Van der Waals
Pancreatic polypeptide L218 5.42x43 TM5 hydrophobic
Pancreatic polypeptide Q222 5.46x461 TM5 polar (hydrogen bond)
Pancreatic polypeptide Q222 5.46x461 TM5 Van der Waals
Pancreatic polypeptide H282 6.52x52 TM6 Van der Waals
Pancreatic polypeptide N285 6.55x55 TM6 polar (hydrogen bond)
Pancreatic polypeptide N285 6.55x55 TM6 Van der Waals
Pancreatic polypeptide E288 6.58x58 TM6 polar (charge-assisted hydrogen bond)
Pancreatic polypeptide D289 6.59x59 TM6 polar (charge-assisted hydrogen bond)
Pancreatic polypeptide H292 ECL3 Van der Waals
Pancreatic polypeptide H292 ECL3 polar (hydrogen bond with backbone)
Pancreatic polypeptide E293 ECL3 polar (charge-assisted hydrogen bond)
Pancreatic polypeptide I297 ECL3 hydrophobic
Pancreatic polypeptide I297 ECL3 Van der Waals
Pancreatic polypeptide N301 7.32x31 TM7 polar (hydrogen bond)
Pancreatic polypeptide N301 7.32x31 TM7 polar (hydrogen bond)
Pancreatic polypeptide N301 7.32x31 TM7 Van der Waals
Pancreatic polypeptide F304 7.35x34 TM7 hydrophobic
Pancreatic polypeptide F304 7.35x34 TM7 Van der Waals
Pancreatic polypeptide H308 7.39x38 TM7 polar (hydrogen bond)
Pancreatic polypeptide H308 7.39x38 TM7 Van der Waals

Ligands

Pancreatic polypeptide

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Residue Diagrams

L N G L V G V V T E I S Y S T V I F V M 1 A N L A F S D F L M C L L C Q P L T A V Y 2 L V L S L I S V T V S M C Q I F A S M K 3 A Y L G I V L I W V I A C V L S L P F 4 Y C V L I F G L P L C Y Q F L L L F T T Y 5 V V M V V A F A V L W L P L H V F N S L 6 F P N V C T S A M A L L H C V L F I L 7
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ICL1 K E K A ICL1ECL1 Y W I F ECL1ICL2 P T G W K P ICL2ECL2 I L E N V F H K N H S K A L E F L A D K V V C T E S W P ECL2ICL3 H K G T Y ICL3ECL3 H E A I P ECL3N-term M N T S H L L A L L L P K S P Q G E N R S K P L G T P Y N F S E H C Q D N-termC-term L T C Q Q S A P L E E S E H L P L S T V H T E V S K G S L R L S G R S N P I C-term S V D V M V F I V T S Y S I E T V V G V L G N L C L M C V T V R Q N V T N L L I A N L A F S D F L M C L L C Q P L T A V Y T I M D G E T L C K M S A F I Q C M S V T V S I L S L V L V A L E R H Q L I I N S I S Q A Y L G I V L I W V I A C V L S L P F L A N S L A H H R T I Y T T F L L L F Q Y C L P L G F I L V C Y A R I Y R R L Q R Q G R V F S L R A G H M K Q V N V V L V V M V V A F A V L W L P L H V F N S L E D W H I C H G N L I F L V C H L L A M A S T C V N P F I Y G F L N T N I K A F K K E L V
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Residue Table


GPCRdb(A)
GPCRdb(A)
Y4 receptor
TM2
2x56 2.57x56 C94
2x60 2.61x60 T98
2x63 2.64x63 Y101
2x64 2.65x64 T102
TM3
3x32 3.32x32 Q121
3x36 3.36x36 V125
TM4
4x61 4.60x61 F174
ECL2
45x51 45.51x51 T202
TM5
5x36 5.35x36 R211
5x40 5.39x40 T215
5x43 5.42x43 L218
5x461 5.46x461 Q222
TM6
6x52 6.52x52 H282
6x55 6.55x55 N285
6x58 6.58x58 E288
6x59 6.59x59 D289
TM7
7x31 7.32x31 N301
7x34 7.35x34 F304
7x38 7.39x38 H308