PDB
7XMT
Resolution
2.8 Å
Released
Aug. 3, 2022
Receptor
SST4
Class
A
Species
Homo sapiens
Ligand
Function
J-2156
Agonist
Reference
10.1038/S41422-022-00679-X

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
J-2156 S99 2.56x56 TM2 Van der Waals
J-2156 V103 2.60x60 TM2 hydrophobic
J-2156 W112 23.50x50 ECL1 hydrophobic
J-2156 V122 3.28x28 TM3 Van der Waals
J-2156 L123 3.29x29 TM3 hydrophobic
J-2156 D126 3.32x32 TM3 polar (charge-charge)
J-2156 G127 3.33x33 TM3 Van der Waals
J-2156 M130 3.36x36 TM3 hydrophobic
J-2156 F131 3.37x37 TM3 hydrophobic
J-2156 I181 4.60x61 TM4 Van der Waals
J-2156 C198 45.50x50 ECL2 Van der Waals
J-2156 N199 45.51x51 ECL2 Van der Waals
J-2156 L200 45.52x52 ECL2 Van der Waals
J-2156 V212 5.39x40 TM5 hydrophobic
J-2156 T215 5.42x43 TM5 hydrophobic
J-2156 F275 6.51x51 TM6 aromatic (edge-to-face)
J-2156 Y276 6.52x52 TM6 hydrophobic
J-2156 Q279 6.55x55 TM6 hydrophobic
J-2156 L297 7.39x38 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 A K M K ICL1ECL1 R H W P F ECL1ICL2 P L R A A T Y R ICL2ECL2 D T R P A R G G Q A V A C N L Q W P ECL2ICL3 A L R A G ICL3ECL3 T S L D ECL3N-term M S A P S T L P P G G E E G L G T A W P S A A N A S S A P A E A E E A V A G P G D A R N-termC-term L R C C L L E G A G G A E E E P L D Y Y A T A L K S K G G A G C M C P P L P C Q Q E A L Q P E P G R K R I P L T R T T T F C-term A A G M V A I Q C I Y A L V C L V G L V G N A L V I F V I L R Y T A T N I Y L L N L A V A D E L F M L S V P F V A S S A A L G S V L C R A V L S V D G L N M F T S V F C L T V L S V D R Y V A V V H R P S V A K L I N L G V W L A S L L V T L P I A I F A H P A W S A V F V V Y T F L L G F L L P V L A I G L C Y L L I V G K M R A V W Q Q R R R S E K K I T R L V L M V V V V F V L C W M P F Y V V Q L L N L F V A T V N H V S L I L S Y A N S C A N P I L Y G F L S D N F Q R F R R F V L C
Helix box plot — Download: PNG | SVG A N G V L G V L C V L A Y I C Q I A V M 1 L N L A V A D E L F M L S V P F V A S S 2 V T L C F V S T F M N L G D V S L V A R 3 A K L I N L G V W L A S L L V T L P I 4 Y C L G I A L V P L L F G L L F T Y V V F 5 L M V V V V F V L C W M P F Y V V Q L L 6 I P N A C S N A Y S L I L S V H N V T 7

GPCRdb(A)
GPCRdb(A)
SST4 receptor
TM2
2x56 2.56x56 S99
2x60 2.60x60 V103
ECL1
23x50 23.50x50 W112
TM3
3x28 3.28x28 V122
3x29 3.29x29 L123
3x32 3.32x32 D126
3x33 3.33x33 G127
3x36 3.36x36 M130
3x37 3.37x37 F131
TM4
4x61 4.60x61 I181
ECL2
45x50 45.50x50 C198
45x51 45.51x51 N199
45x52 45.52x52 L200
TM5
5x40 5.39x40 V212
5x43 5.42x43 T215
TM6
6x51 6.51x51 F275
6x52 6.52x52 Y276
6x55 6.55x55 Q279
TM7
7x38 7.39x38 L297