PDB
8F76
Resolution
3.1 Å
Released
March 22, 2023
Receptor
OR51E2
Class
O1
Species
Homo sapiens
Ligand
propanoic acid
Function
Agonist
Reference
10.1038/S41586-023-05798-Y

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
propanoic acid L158 4.60x60 TM4 hydrophobic
propanoic acid H180 45.52x52 ECL2 Van der Waals
propanoic acid H180 45.52x52 ECL2 polar (hydrogen bond)
propanoic acid Q181 ECL2 Van der Waals
propanoic acid Q181 ECL2 polar (hydrogen bond)
propanoic acid G198 5.39x40 TM5 polar (hydrogen bond with backbone)
propanoic acid G198 5.39x40 TM5 Van der Waals
propanoic acid I202 5.43x44 TM5 hydrophobic
propanoic acid I202 5.43x44 TM5 Van der Waals
propanoic acid R262 6.59x59 TM6 polar (charge-assisted hydrogen bond)

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R S L H ICL1ECL1 S R E I ECL1ICL2 P L R H A A V L ICL2ECL2 A F C H S N V L S H S Y C V H Q D V M K L A Y A D ECL2ICL3 P ICL3ECL3 N S L ECL3N-term M S S C N F T H A T F V L I G I P G L E K N-termC-term S C D K D L Q A V G G K C-term A H F W V G F P L L S M Y V V A M F G N C I V V F I V R T E A P M Y L F L C M L A A I D L A L S T S T M P K I L A L F W F D S F E A C L T Q M F F I H A L S A I E S T I L L A M A F D R Y V A I C H N N T V T A Q I G I V A V V R G S L F F F P L P L L I K R L T L P N V V Y G L T A I L L V M G V D V M F I S L S Y F L I I R T V L Q L S K S E R A K A F G T C V S H I G V V L A F Y V P L I G L S V V H R F G H P I V R V V M G D I Y L L L P P V I N P I I Y G A K T K Q V L A I R T R M F K I
Helix box plot — Download: PNG | SVG C N G F M A V V Y M S L L P F G V W F H 1 C M L A A I D L A L S T S T M P K I L A 2 A L L I T S E I A S L A H I F F M Q T L 3 T A Q I G I V A V V R G S L F F F P L P 4 Y S L S I F M V D V G M V L L I A T L G Y 5 V S H I G V V L A F Y V P L I G L S V V 6 I P N I V P P L L L Y I D G M V V R V 7

GPCRdb(A)
GPCRdb(A)
OR51E2
TM4
4x60 4.60x60 L158
ECL2
45x52 45.52x52 H180
TM5
5x40 5.39x40 G198
5x44 5.43x44 I202
TM6
6x59 6.59x59 R262