PDB
8G94
Resolution
3.2 Å
Released
April 19, 2023
Receptor
S1P1
Class
A
Species
Homo sapiens
Ligand
Function
Early activation antigen CD69
Allosteric agonist
Reference
10.7554/ELIFE.88204

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Early activation antigen CD69 N157 4.39x39 TM4 hydrophobic
Early activation antigen CD69 L160 4.42x42 TM4 hydrophobic
Early activation antigen CD69 F161 4.43x43 TM4 hydrophobic
Early activation antigen CD69 I164 4.46x46 TM4 hydrophobic
Early activation antigen CD69 S165 4.47x47 TM4 Van der Waals
Early activation antigen CD69 W168 4.50x50 TM4 Van der Waals
Early activation antigen CD69 V169 4.51x51 TM4 hydrophobic
Early activation antigen CD69 L172 4.54x54 TM4 hydrophobic
Early activation antigen CD69 I173 4.55x55 TM4 hydrophobic
Early activation antigen CD69 G176 4.58x58 TM4 Van der Waals
Early activation antigen CD69 I179 4.61x61 TM4 Van der Waals
Early activation antigen CD69 M180 4.62x62 TM4 hydrophobic
Early activation antigen CD69 G181 4.63x63 TM4 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K K F H ICL1ECL1 G A T T Y K L ECL1ICL2 M K L H N G S ICL2ECL2 W N C I S A L S S C S T V L P L Y ECL2ICL3 F R K N I S K A ICL3ECL3 K V K T C ECL3N-term M G P T S V P L V K A H R S S V S D Y V N Y D I I V R H Y N Y T G K L N I S A D K N-termC-term C C K C P S G D S A G K F K R P I I A G M E F S R S K S D N S S H P Q K D E G D N P E T I M S S G N V N S S S C-term E N S I K L T S V V F I L I C C F I I L E N I F V L L T I W K T R P M Y Y F I G N L A L S D L L A G V A Y T A N L L L S T P A Q W F L R E G S M F V A L S A S V F S L L A I A I E R Y I T M L K N N F R L F L L I S A C W V I S L I L G G L P I M G H K H Y I L F C T T V F T L L L L S I V I L Y C R I Y S L V R T R S R R L T S R S S E K S L A L L K T V I I V L S V F I A C W A P L F I L L L L D V G C D I L F R A E Y F L V L A V L N S G T N P I I Y T L T N K E F I R M R R A I M S
Helix box plot — Download: PNG | SVG I N E L I I F C C I L I F V V S T L K I 1 G N L A L S D L L A G V A Y T A N L L L 2 A L L S F V S A S L A V F M S G E R L F 3 L F L L I S A C W V I S L I L G G L P I 4 Y L I V I S L L L L T F V T T C F L I Y 5 I I V L S V F I A C W A P L F I L L L L 6 I P N T G S N L V A L V L F Y E A R F 7

GPCRdb(A)
GPCRdb(A)
S1P1 receptor
TM4
4x39 4.39x39 N157
4x42 4.42x42 L160
4x43 4.43x43 F161
4x46 4.46x46 I164
4x47 4.47x47 S165
4x50 4.50x50 W168
4x51 4.51x51 V169
4x54 4.54x54 L172
4x55 4.55x55 I173
4x58 4.58x58 G176
4x61 4.61x61 I179
4x62 4.62x62 M180
4x63 4.63x63 G181