PDB
8HNM
Resolution
2.9 Å
Released
Nov. 29, 2023
Receptor
CXCR3
Class
A
Species
Homo sapiens
Ligand
Function
CHEMBL2220409
Agonist
Reference
10.1038/S41594-023-01175-5

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL2220409 Y60 1.39x39 TM1 hydrophobic
CHEMBL2220409 L102 2.53x53 TM2 hydrophobic
CHEMBL2220409 L106 2.57x57 TM2 Van der Waals
CHEMBL2220409 W109 2.60x60 TM2 hydrophobic
CHEMBL2220409 A110 2.61x61 TM2 Van der Waals
CHEMBL2220409 A113 2.64x64 TM2 hydrophobic
CHEMBL2220409 F131 3.32x32 TM3 hydrophobic
CHEMBL2220409 F135 3.36x36 TM3 aromatic (edge-to-face)
CHEMBL2220409 F135 3.36x36 TM3 hydrophobic
CHEMBL2220409 W268 6.48x48 TM6 aromatic (edge-to-face)
CHEMBL2220409 Y271 6.51x51 TM6 hydrophobic
CHEMBL2220409 Y271 6.51x51 TM6 aromatic (edge-to-face)
CHEMBL2220409 H272 6.52x52 TM6 Van der Waals
CHEMBL2220409 S304 7.39x38 TM7 Van der Waals
CHEMBL2220409 G307 7.42x41 TM7 Van der Waals
CHEMBL2220409 Y308 7.43x42 TM7 hydrophobic
CHEMBL2220409 C311 7.46x46 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
Helix box plot — Download: PNG | SVG G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7

GPCRdb(A)
GPCRdb(A)
CXCR3
TM1
1x39 1.39x39 Y60
TM2
2x53 2.53x53 L102
2x57 2.57x57 L106
2x60 2.60x60 W109
2x61 2.61x61 A110
2x64 2.64x64 A113
TM3
3x32 3.32x32 F131
3x36 3.36x36 F135
TM6
6x48 6.48x48 W268
6x51 6.51x51 Y271
6x52 6.52x52 H272
TM7
7x38 7.39x38 S304
7x41 7.42x41 G307
7x42 7.43x42 Y308
7x46 7.46x46 C311