PDB
8HNN
Resolution
3.6 Å
Released
Nov. 29, 2023
Receptor
CXCR3
Class
A
Species
Homo sapiens
Ligand
CHEMBL1921858
Function
Allosteric antagonist
Reference
10.1038/S41594-023-01175-5

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL1921858 F224 5.47x47 TM5 hydrophobic
CHEMBL1921858 L228 5.51x51 TM5 hydrophobic
CHEMBL1921858 M231 5.54x54 TM5 hydrophobic
CHEMBL1921858 Y235 5.58x58 TM5 hydrophobic
CHEMBL1921858 L239 5.62x62 TM5 hydrophobic
CHEMBL1921858 V266 6.38x38 TM6 hydrophobic
CHEMBL1921858 A273 6.45x45 TM6 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
Helix box plot — Download: PNG | SVG G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7

GPCRdb(A)
GPCRdb(A)
CXCR3
TM5
5x47 5.47x47 F224
5x51 5.51x51 L228
5x54 5.54x54 M231
5x58 5.58x58 Y235
5x62 5.62x62 L239
TM6
6x38 6.38x38 V258
6x45 6.45x45 A265