PDB
8UY0
Resolution
3.2 Å
Released
Oct. 30, 2024
Receptor
OR2T2
Class
O2
Species
Homo sapiens
Ligand
S-carvone
Function
Agonist
Reference
10.1038/S41586-024-08126-0

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Ligand Amino Acid Generic Number Segment Interaction Type
S-carvone Y103 3.32x32 TM3 hydrophobic
S-carvone Y258 ECL3 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 S R L H ICL1ECL1 K D K T I ECL1ICL2 P L R Y P L L M ICL2ECL2 P F C R S R E I N H F F C E I P A V L K L S C T D ECL2ICL3 M N ICL3ECL3 P H S Y H ECL3N-term M G M E G L L Q N S T N F V L T G L I T H P A N-termC-term K G C-term F P G L L F A I V F S I F V V A I T A N L V M I L L I H M D T P M Y F L L S Q L S I M D T I Y I C I T V P K M L Q D L L S S F L G C A V Q I F L Y L T L I G G E F F L L G L M A Y D R Y V A V C N N R R V C L F M V V G S W V G G S L D G F M L T P V T M S F T S L Y E T L M Y A C C V L M L L I P L S V I S V S Y T H I L L T V H R S A E G R R K A F A T C S S H I M V V S V F Y G A A F Y T N V L T P E K D K V V S A F Y T I L T P M L N P L I Y S L R N K D L R K C G S R V A V A A A V L G R S Q S I T V I R
Helix box plot — Download: PNG | SVG L N A T I A V V F I S F V I A F L L G P 1 S Q L S I M D T I Y I C I T V P K M L Q 2 L G L L F F E G G I L T L Y L F I Q V A 3 C L F M V V G S W V G G S L D G F M L T 4 Y S V S I V S L P I L L M L V C C A Y M 5 S S H I M V V S V F Y G A A F Y T N V L 6 L P N L M P T L I T Y F A S V V K D K 7

GPCRdb(A)
GPCRdb(A)
OR2T2
TM3
3x32 3.32x32 Y105