PDB
8WC4
Resolution
3.1 Å
Released
Dec. 27, 2023
Receptor
TA1
Class
A
Species
Mus musculus
Ligand
CHEMBL476516
Function
Agonist
Reference
10.1016/J.CELL.2023.10.014

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL476516 D102 3.32x32 TM3 polar (charge-assisted hydrogen bond)
CHEMBL476516 I103 3.33x33 TM3 hydrophobic
CHEMBL476516 I103 3.33x33 TM3 Van der Waals
CHEMBL476516 S106 3.36x36 TM3 Van der Waals
CHEMBL476516 F264 6.51x51 TM6 aromatic (edge-to-face)
CHEMBL476516 F264 6.51x51 TM6 Van der Waals
CHEMBL476516 F265 6.52x52 TM6 hydrophobic
CHEMBL476516 F265 6.52x52 TM6 Van der Waals
CHEMBL476516 Y287 7.39x38 TM7 hydrophobic
CHEMBL476516 Y287 7.39x38 TM7 Van der Waals
CHEMBL476516 Y291 7.43x42 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K Q L H ICL1ECL1 C W Y F ECL1ICL2 P L R Y K A K I ICL2ECL2 L N L K G V E E L Y R S Q V S D L G G C S P F F ECL2ICL3 L E G K S Q ICL3ECL3 Y V I ECL3N-term M H L C H A I T N I S H R N S D W S R E N-termC-term G K I F Q K D S S R S K L F L C-term V Q A S L Y S L M S L I I L A T L V G N L I V I I S I S H F T P T N W L L H S M A I V D F L L G C L I M P C S M V R T V E R G E I L C K V H T S T D I M L S S A S I F H L A F I S I D R Y C A V C D N I S T I L V M I L V S W S L P A V Y A F G M I F L E S K V S G V L A F M T S F Y I P G S V M L F V Y Y R I Y F I A K G Q A R S I N R T N V Q V G A P Q S K E T K A A K T L G I M V G V F L V C W C P F F L C T V L D P F L G P P S L N D A L Y W F G Y L N S A L N P M V Y A F F Y P W L K M F R R A V L L
Helix box plot — Download: PNG | SVG L N G V L T A L I I L S M L S Y L S A Q 1 H S M A I V D F L L G L C I M P C S M V R 2 F A L H F I S A S S L M I D T S T H V K 3 I L V M I L V S W S L P A V Y A F G M I 4 Y V F L M V S G P I Y F S T M F A L V G S 5 G I M V G V F L V C W C P F F L C T V L 6 M P N L A S N L Y G F W Y L A D N L S 7

GPCRdb(A)
GPCRdb(A)
TA1 receptor
TM3
3x32 3.32x32 D102
3x33 3.33x33 I103
3x36 3.36x36 S106
TM6
6x51 6.51x51 F264
6x52 6.52x52 F265
TM7
7x38 7.39x38 Y287
7x42 7.43x42 Y291