PDB
8XWS
Resolution
3.1 Å
Released
Jan. 15, 2025
Receptor
CXCR2
Class
A
Species
Homo sapiens
Ligand
CXCL5
Function
Agonist
Reference
10.1016/J.MOLCEL.2025.01.024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CXCL5 L33 N-term Van der Waals
CXCL5 L33 N-term hydrophobic
CXCL5 D35 N-term polar (charge-assisted hydrogen bond)
CXCL5 A36 N-term hydrophobic
CXCL5 A36 N-term Van der Waals
CXCL5 P38 N-term Van der Waals
CXCL5 P38 N-term hydrophobic
CXCL5 V187 ECL2 hydrophobic
CXCL5 V187 ECL2 Van der Waals
CXCL5 S189 ECL2 polar (hydrogen bond)
CXCL5 S190 ECL2 Van der Waals
CXCL5 N191 ECL2 Van der Waals
CXCL5 Y197 45.51x51 ECL2 hydrophobic
CXCL5 Y197 45.51x51 ECL2 Van der Waals
CXCL5 E198 45.52x52 ECL2 Van der Waals
CXCL5 D199 ECL2 Van der Waals
CXCL5 N202 ECL2 Van der Waals
CXCL5 R208 5.35x36 TM5 polar (charge-assisted hydrogen bond)
CXCL5 R212 5.39x40 TM5 polar (charge-assisted hydrogen bond)
CXCL5 D274 6.58x58 TM6 polar (charge-assisted hydrogen bond)
CXCL5 R278 6.62x62 TM6 polar (charge-assisted hydrogen bond)
CXCL5 E284 ECL3 Van der Waals
CXCL5 R289 7.28x27 TM7 polar (charge-assisted hydrogen bond)
CXCL5 D293 7.32x31 TM7 polar (charge-assisted hydrogen bond)
CXCL5 L296 7.35x34 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R V G R ICL1ECL1 G W I F ECL1ICL2 A T R T L T Q K R Y ICL2ECL2 R T V Y S S N V S P A C Y E D M G N ECL2ICL3 H M G ICL3ECL3 V I Q E ECL3N-term M E D F N M E S D S F E D F W K G E D L S N Y S Y S S T L P P F L L D A A P C E P E S L N-termC-term G L I S K D S L P K D S R P S F V G S S S G H T S T T L C-term E I N K Y F V V I I Y A L V F L L S L L G N S L V M L V I L Y S S V T D V Y L L N L A L A D L L F A L T L P I W A A S K V N G T F L C K V V S L L K E V N F Y S G I L L L A C I S V D R Y L A I V H L V K F I C L S I W G L S L L L A L P V L L F R N T A N W R M L L R I L P Q S F G F I V P L L I M L F C Y G F T L R T L F K A Q K H R A M R V I F A V V L I F L L C W L P Y N L V L L A D T L M R T Q T C E R R N H I D R A L D A T E I L G I L H S C L N P L I Y A F I G Q K L L K H F R H G I L A I
Helix box plot — Download: PNG | SVG S N G L L S L L F V L A Y I I V V F Y K 1 L N L A L A D L L F A L T L P I W A A S 2 C A L L L I G S Y F N V E K L L S V V K 3 V K F I C L S I W G L S L L L A L P V 4 Y C F L M I L L P V I F G F S Q P L I R L 5 F A V V L I F L L C W L P Y N L V L L A 6 L P N L C S H L I G L I E T A D L A R 7

GPCRdb(A)
GPCRdb(A)
CXCR2
ECL2
45x51 45.51x51 Y197
45x52 45.52x52 E198
TM5
5x36 5.35x36 R208
5x40 5.39x40 R212
TM6
6x58 6.58x58 D274
6x62 6.62x62 R278
TM7
7x27 7.28x27 R289
7x31 7.32x31 D293
7x34 7.35x34 L296