Structure information

apelin receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8XZI

SPECIES

Homo sapiens

RESOLUTION

2.700

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

March 20, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CMF-019 Y35 1.39x39 TM1 polar (hydrogen bond)
CMF-019 F78 2.53x53 TM2 hydrophobic
CMF-019 F78 2.53x53 TM2 Van der Waals
CMF-019 L82 2.57x57 TM2 Van der Waals
CMF-019 W85 2.60x60 TM2 polar (hydrogen bond)
CMF-019 S106 3.29x29 TM3 polar (hydrogen bond)
CMF-019 I109 3.32x32 TM3 Van der Waals
CMF-019 I109 3.32x32 TM3 hydrophobic
CMF-019 F110 3.33x33 TM3 Van der Waals
CMF-019 F110 3.33x33 TM3 hydrophobic
CMF-019 M113 3.36x36 TM3 polar (hydrogen bond)
CMF-019 R168 4.64x65 TM4 polar (charge-assisted hydrogen bond)
CMF-019 W261 6.48x48 TM6 Van der Waals
CMF-019 W261 6.48x48 TM6 hydrophobic
CMF-019 Y264 6.51x51 TM6 aromatic (edge-to-face)
CMF-019 Y264 6.51x51 TM6 polar (hydrogen bond)
CMF-019 Y264 6.51x51 TM6 polar (hydrogen bond)
CMF-019 V267 6.54x54 TM6 Van der Waals
CMF-019 K268 6.55x55 TM6 Van der Waals
CMF-019 Y271 6.58x58 TM6 polar (hydrogen bond)
CMF-019 L287 7.31x30 TM7 Van der Waals
CMF-019 L287 7.31x30 TM7 polar (hydrogen bond with backbone)
CMF-019 M288 7.32x31 TM7 Van der Waals
CMF-019 M288 7.32x31 TM7 hydrophobic
CMF-019 F291 7.35x34 TM7 hydrophobic
CMF-019 F291 7.35x34 TM7 Van der Waals
CMF-019 T295 7.39x38 TM7 polar (hydrogen bond with backbone)
CMF-019 T295 7.39x38 TM7 polar (hydrogen bond)
CMF-019 S298 7.42x41 TM7 polar (hydrogen bond)
CMF-019 Y299 7.43x42 TM7 polar (hydrogen bond)
CMF-019 Y299 7.43x42 TM7 aromatic (face-to-edge)

Ligands

CMF-019

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N G T T G L L F V L M Y I A P I L A 1 A S L A V A D L T F V V T L P L W A T Y 2 G T L C F V S A Y M N V F I L Y S S L K 3 G A V A T A V L W V L A A L L A M P V 4 Y C T L M I T F P V V F G V T T S S V G L 5 V V L V V T F A L C W M P Y H L V K T L 6 F P N L C S N V Y S I C T C Y P F I N 7
Download: PNG | SVG
ICL1 S R E K R ICL1ECL1 Y D W P F ECL1ICL2 P V A N A R L R ICL2ECL2 T T G D L E N T T K V Q C Y M D Y S M V A T V S ECL2ICL3 R K E ICL3ECL3 L H W ECL3N-term M E E G G D F D N Y Y G A D N Q S E C E Y T D W K S S G N-termC-term Q S R C A G T S H S S S G E K S A S Y S S G H S Q G P G P N M G K G G E Q M H E K S I P Y S Q E T L V V D C-term A L I P A I Y M L V F L L G T T G N G L V L W T V F R S R S A D I F I A S L A V A D L T F V V T L P L W A T Y T Y R D G T F F C K L S S Y L I F V N M Y A S V F C L T G L S F D R Y L A I V R L R V S G A V A T A V L W V L A A L L A M P V M V L R S E W A W E V G L G V S S T T V G F V V P F T I M L T C Y F F I A Q T I A G H F R I E G L R K R R R L L S I I V V L V V T F A L C W M P Y H L V K T L Y M L G S L P C D F D L F L M N I F P Y C T C I S Y V N S C L N P F L Y A F F D P R C T S G F R Q A M L C C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
apelin receptor
TM1
1x39 1.39x39 Y35
TM2
2x53 2.53x53 F78
2x57 2.57x57 L82
2x60 2.60x60 W85
TM3
3x29 3.29x29 S106
3x32 3.32x32 I109
3x33 3.33x33 F110
3x36 3.36x36 M113
TM4
4x65 4.64x65 R168
TM6
6x48 6.48x48 W261
6x51 6.51x51 Y264
6x54 6.54x54 V267
6x55 6.55x55 K268
6x58 6.58x58 Y271
TM7
7x30 7.31x30 L287
7x31 7.32x31 M288
7x34 7.35x34 F291
7x38 7.39x38 T295
7x41 7.42x41 S298
7x42 7.43x42 Y299