Structure information

TA1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8ZSP

SPECIES

Homo sapiens

RESOLUTION

3.140

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELREP.2024.114505

PUBLICATION DATE

July 24, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Lysergide D103 3.32x32 TM3 polar (charge-assisted hydrogen bond)
Lysergide I104 3.33x33 TM3 hydrophobic
Lysergide I104 3.33x33 TM3 Van der Waals
Lysergide S107 3.36x36 TM3 Van der Waals
Lysergide S108 3.37x37 TM3 polar (hydrogen bond)
Lysergide S183 45.51x51 ECL2 Van der Waals
Lysergide V184 45.52x52 ECL2 Van der Waals
Lysergide V184 45.52x52 ECL2 hydrophobic
Lysergide F186 ECL2 Van der Waals
Lysergide F186 ECL2 hydrophobic
Lysergide T194 5.42x43 TM5 Van der Waals
Lysergide S198 5.46x461 TM5 polar (hydrogen bond)
Lysergide W264 6.48x48 TM6 hydrophobic
Lysergide W264 6.48x48 TM6 Van der Waals
Lysergide F267 6.51x51 TM6 hydrophobic
Lysergide F267 6.51x51 TM6 Van der Waals
Lysergide F268 6.52x52 TM6 aromatic (edge-to-face)
Lysergide F268 6.52x52 TM6 Van der Waals
Lysergide I290 7.39x38 TM7 Van der Waals
Lysergide I290 7.39x38 TM7 hydrophobic
Lysergide Y294 7.43x42 TM7 Van der Waals

Ligands

Lysergide

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

L N G V L T T L I I L V M L S Y L S A R 1 H S M A T V D F L L G L C V M P Y S M V R 2 F S L H F I S A S S L M I D T S T H I K 3 I C V M I F I S W S V P A V F A F G M I 4 Y V C L M I S G P I Y F S T M F T L V G S 5 G I V M G V F L I C W C P F F I C T V M 6 M P N F T S N L Y G F W I L V D N L T 7
Download: PNG | SVG
ICL1 K Q L H ICL1ECL1 C W Y F ECL1ICL2 P L R Y K A K M ICL2ECL2 L N F K G A E E I Y Y K H V H C R G G C S V F F ECL2ICL3 I G L E M K ICL3ECL3 H Y I I ECL3N-term M M P F C H N I I N I S C V K N N W S N N-termC-term G K I F Q K D S S R C K L F L E L S S C-term D V R A S L Y S L M V L I I L T T L V G N L I V I V S I S H F T P T N W L I H S M A T V D F L L G C L V M P Y S M V R S A E H G E V F C K I H T S T D I M L S S A S I F H L S F I S I D R Y Y A V C D N I L V I C V M I F I S W S V P A V F A F G M I F L E S K I S G V L T F M T S F Y I P G S I M L C V Y Y R I Y L I A K E Q A R L I S D A N Q K L Q N G I S Q S K E R K A V K T L G I V M G V F L I C W C P F F I C T V M D P F L P P T L N D V L I W F G Y L N S T F N P M V Y A F F Y P W L K M F R K A M L F
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
TA1 receptor
TM3
3x32 3.32x32 D103
3x33 3.33x33 I104
3x36 3.36x36 S107
3x37 3.37x37 S108
ECL2
45x51 45.51x51 S183
45x52 45.52x52 V184
TM5
5x43 5.42x43 T194
5x461 5.46x461 S198
TM6
6x48 6.48x48 W264
6x51 6.51x51 F267
6x52 6.52x52 F268
TM7
7x38 7.39x38 I290
7x42 7.43x42 Y294