PDB
8ZX5
Resolution
3.0 Å
Released
Nov. 13, 2024
Receptor
GPR55
Class
A
Species
Homo sapiens
Ligand
AM251
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
AM251 Y101 3.32x32 TM3 hydrophobic
AM251 F102 3.33x33 TM3 hydrophobic
AM251 F169 45.51x51 ECL2 hydrophobic
AM251 W177 ECL2 hydrophobic
AM251 F246 6.55x55 TM6 hydrophobic
AM251 M274 7.39x38 TM7 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 W P D Y ICL1ECL1 Q S P ECL1ICL2 P L L V S H L R ICL2ECL2 K Y M C F H N M S D D T W ECL2ICL3 T Q D W V Q ICL3ECL3 F I V ECL3N-term M S Q Q N T S G D C L N-termC-term V Q L V L Q D T T I S R G C-term F D G V N E L M K T L Q F A V H I P T F V L G L L L N L L A I H G F S T F L K N R A A T S I Y M I N L A V F D L L L V L S L P F K M V L S Q V F P S L C T L V E C L Y F V S M Y G S V F T I C F I S M D R F L A I R Y S P R K I F G I C C T I W V L V W T G S I P I Y S F H G K V E S A K V F F P L E V F G F L L P M G I M G F C C S R S I H I L L G R R D H Q K A C I Y S I A A S L A V F V V S F L P V H L G F F L Q F L V R N S E C R A K Q S I S F F L Q L S M C F S N V N C C L D V F C Y Y F V I K E I R A R F R M N H R P S
Helix box plot — Download: PNG | SVG L N L L L G L V F T P I H V A F Q L T K 1 I N L A V F D L L L V L S L P F K M V L 2 F C I T F V S G Y M S V F Y L C E V L T 3 I F G I C C T I W V L V W T G S I P I 4 C C F G M I G M P L L F G F V E L P F F V 5 A A S L A V F V V S F L P V H L G F F L 6 F V D L C C N V N S F C M S L Q L F F 7

GPCRdb(A)
GPCRdb(A)
GPR55
TM3
3x32 3.32x32 Y101
3x33 3.33x33 F102
ECL2
45x51 45.51x51 F169
TM6
6x55 6.55x55 F246
TM7
7x38 7.39x38 M274