PDB
9EBH
Resolution
3.6 Å
Released
Aug. 20, 2025
Receptor
A3
Class
A
Species
Homo sapiens
Ligand
Function
adenosine
Agonist
Reference
10.1038/S41467-025-62872-X

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
adenosine L90 3.32x32 TM3 Van der Waals
adenosine L91 3.33x33 TM3 Van der Waals
adenosine T94 3.36x36 TM3 Van der Waals
adenosine F168 45.52x52 ECL2 aromatic (face-to-face)
adenosine M177 5.38x40 TM5 Van der Waals
adenosine W243 6.48x48 TM6 Van der Waals
adenosine L246 6.51x51 TM6 Van der Waals
adenosine N250 6.55x55 TM6 polar (hydrogen bond)
adenosine L264 7.35x34 TM7 Van der Waals
adenosine I268 7.39x38 TM7 Van der Waals
adenosine S271 7.42x41 TM7 polar (hydrogen bond)
adenosine H272 7.43x42 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 P S L Q ICL1ECL1 I T I ECL1ICL2 T V R Y K R V T ICL2ECL2 W N M K L T S E Y H R N V T F L S C Q F V S V M ECL2ICL3 S N S K ICL3ECL3 G E V ECL3N-term M P N N S T A L N-termC-term L D T S I E K N S E C-term S L A N V T Y I T M E I F I G L C A I V G N V L V I C V V K L N T T T F Y F I V S L A L A D I A V G V L V M P L A I V V S L G H F Y S C L F M T C L L L I F T H A S I M S L L A I A V D R Y L R V K L T H R R I W L A L G L C W L V S F L V G L T P M F G R M D Y M V Y F S F L T W I F I P L V V M C A I Y L D I F Y I I R N K L S L N L E T G A F Y G R E F K T A K S L F L V L F L F A L S W L P L S I I N C I I Y F N P Q L V L Y M G I L L S H A N S M M N P I V Y A Y K I K K Y L L C V V D S F K E T I L K A C H P S
Helix box plot — Download: PNG | SVG V N G V I A C L G I F I E M T I Y T V N 1 V S L A L A D I A V G L V V M P L A I V V 2 A L L S M I S A H T F I L L L C T M F L 3 I W L A L G L C W L V S F L V G L T P M 4 Y I A C M V V L P I F I W T L F S F Y V M Y 5 F L V L F L F A L S W L P L S I I N C I 6 I P N M M S N A H S L L I G M Y L V L 7

GPCRdb(A)
GPCRdb(A)
A3 receptor
TM3
3x32 3.32x32 L90
3x33 3.33x33 L91
3x36 3.36x36 T94
ECL2
45x52 45.52x52 F168
TM5
5x40 5.38x40 M177
TM6
6x48 6.48x48 W243
6x51 6.51x51 L246
6x55 6.55x55 N250
TM7
7x34 7.35x34 L264
7x38 7.39x38 I268
7x41 7.42x41 S271
7x42 7.43x42 H272