PDB
9EPP
Resolution
4.1 Å
Released
Oct. 23, 2024
Receptor
Rhodopsin
Class
A
Species
Hasarius adansoni
Ligand
Function
11,20-Ethanoretinal
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
11,20-Ethanoretinal M99 2.53x53 TM2 Van der Waals
11,20-Ethanoretinal M103 2.57x57 TM2 hydrophobic
11,20-Ethanoretinal Y126 3.28x28 TM3 Van der Waals
11,20-Ethanoretinal G130 3.32x32 TM3 Van der Waals
11,20-Ethanoretinal S131 3.33x33 TM3 Van der Waals
11,20-Ethanoretinal G134 3.36x36 TM3 Van der Waals
11,20-Ethanoretinal T201 45.51x51 ECL2 Van der Waals
11,20-Ethanoretinal I202 45.52x52 ECL2 hydrophobic
11,20-Ethanoretinal L215 5.39x40 TM5 hydrophobic
11,20-Ethanoretinal Y218 5.42x43 TM5 Van der Waals
11,20-Ethanoretinal Y223 5.47x47 TM5 Van der Waals
11,20-Ethanoretinal W290 6.48x48 TM6 hydrophobic
11,20-Ethanoretinal Y293 6.51x51 TM6 hydrophobic
11,20-Ethanoretinal L294 6.52x52 TM6 Van der Waals
11,20-Ethanoretinal A317 7.39x38 TM7 Van der Waals
11,20-Ethanoretinal K321 7.43x42 TM7 covalent bond

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Snake plot — Download: PNG | SVG
ICL1 K N L R ICL1ECL1 T W V I ECL1ICL2 G M A G K P L ICL2ECL2 G W S R Y V P E G S M T S C T I D Y I D T ECL2ICL3 I K S L R S ICL3ECL3 D R T W L ECL3N-term M L P H A A K M A A R V A G D H D G R N I S I V D L L P E D M L P M I H E H W Y K F P P M N-termC-term P C L K C G S D S P K G D S A S T V A E S E K A G E C-term E T S M H Y I L G M L I I V I G I I S V S G N G V V M Y L M M T V T P G N F L V L N L A L S D F G M L F F M M P T M S I N C F A E G P F M C E L Y G M I G S L F G S A S I W S L V M I T L D R Y N V I V K T K V G A L L R M L F V W I W S L G W T I A P M Y A I N P M S Y L I A Y A I F V Y F V P L F I I I Y C Y A F I V M Q V A A H E K S L R E Q A K K M N N E D N K K A S A E F R L A K V A F M T I C C W F M A W T P Y L T L S F L G I F S T P M T S V W G A I F A K A S A C Y N P I V Y G I S H P K L H D Y R A A K F
Helix box plot — Download: PNG | SVG G N G S V S I I G I V I I L M G L I Y H 1 L N L A L S D F G M L F F M M P T M S I 2 M V L S W I S A S G F L S G I M G Y L E 3 A L L R M L F V W I W S L G W T I A P M 4 Y C Y I I I F L P V F Y V F I A Y A I L Y 5 F M T I C C W F M A W T P Y L T L S F L 6 I P N Y C A S A K A F I A G W V S T M 7

GPCRdb(A)
GPCRdb(A)
Rhodopsin
TM2
2x53 2.53x53 M99
2x57 2.57x57 M103
TM3
3x28 3.28x28 Y126
3x32 3.32x32 G130
3x33 3.33x33 S131
3x36 3.36x36 G134
ECL2
45x51 45.51x51 T201
45x52 45.52x52 I202
TM5
5x40 5.39x40 L215
5x43 5.42x43 Y218
5x47 5.47x47 Y223
TM6
6x48 6.48x48 W290
6x51 6.51x51 Y293
6x52 6.52x52 L294
TM7
7x38 7.39x38 A317
7x42 7.43x42 K321