PDB
9JCQ
Resolution
2.6 Å
Released
July 9, 2025
Receptor
GPR4
Class
A
Species
Homo sapiens
Ligand
Function
Lysophosphatidylcholine (LPC)
PAM
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
Lysophosphatidylcholine (LPC) V113 3.48x48 TM3 Van der Waals
Lysophosphatidylcholine (LPC) Y116 3.51x51 TM3 Van der Waals
Lysophosphatidylcholine (LPC) L196 5.53x53 TM5 Van der Waals
Lysophosphatidylcholine (LPC) L199 5.56x56 TM5 Van der Waals
Lysophosphatidylcholine (LPC) S200 5.57x57 TM5 polar (hydrogen bond)
Lysophosphatidylcholine (LPC) R202 5.59x59 TM5 Van der Waals
Lysophosphatidylcholine (LPC) G203 5.60x60 TM5 Van der Waals
Lysophosphatidylcholine (LPC) R206 5.63x63 TM5 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 R ICL1ECL1 D N W I H ECL1ICL2 P L R F A R L R ICL2ECL2 D E L F R D R Y N H T F C F E K F P M ECL2ICL3 S V S T ICL3ECL3 W D ECL3N-term M G N H T W E G C H V N-termC-term F L A S D K P Q E M A N A S L T L E T P L T S K R N S T A K A M T G S W A A T P P S Q G D Q V Q L K M L P P A Q C-term D S R V D H L F P P S L Y I F V I G V G L P T N C L A L W A A Y R Q V Q Q N E L G V Y L M N L S I A D L L Y I C T L P L W V D Y F L H H G P G S C K L F G F I F Y T N I Y I S I A F L C C I S V D R Y L A V A H R V K T A V A V S S V V W A T E L G A N S A P L F H E G W V A W M N L Y R V F V G F L F P W A L M L L S Y R G I L R A V R G E R Q E K A K I K R L A L S L I A I V L V C F A P Y H V L L L S R S A I Y L G R P C G F E E R V F S A Y H S S L A F T S L N C V A D P I L Y C L V N E G V A K L L R A R S D A L H N
Helix box plot — Download: PNG | SVG C N T P L G V G I V F I Y L S P P F L H 1 M N L S I A D L L Y I C T L P L W V D Y 2 C C L F A I S I Y I N T Y F I F G F L K 3 A V A V S S V V W A T E L G A N S A P L 4 Y S L L M L A W P F L F G V F V R Y L N M 5 L S L I A I V L V C F A P Y H V L L L S 6 I P D A V C N L S T F A L S S H Y A S 7

GPCRdb(A)
GPCRdb(A)
GPR4
TM3
3x48 3.48x48 V113
3x51 3.51x51 Y116
TM5
5x53 5.53x53 L196
5x56 5.56x56 L199
5x57 5.57x57 S200
5x59 5.59x59 R202
5x60 5.60x60 G203
5x63 5.63x63 R206