PDB
9JKV
Resolution
3.3 Å
Released
Oct. 29, 2025
Receptor
HCA3
Class
A
Species
Homo sapiens
Ligand
Function
IBC 293
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
IBC 293 V83 2.60x60 TM2 hydrophobic
IBC 293 W93 23.50x50 ECL1 aromatic (edge-to-face)
IBC 293 L104 3.29x29 TM3 Van der Waals
IBC 293 F107 3.32x32 TM3 hydrophobic
IBC 293 L280 7.39x38 TM7 Van der Waals
IBC 293 Y284 7.43x42 TM7 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 L K S W ICL1ECL1 R S D W K F ECL1ICL2 P H H A L N K I ICL2ECL2 L L I Q N G T A N V C I S F S I C H T F ECL2ICL3 Q M D R H A ICL3ECL3 G T Q N C E ECL3N-term M N R H H L Q D H F L E I D K K N C C V F R N-termC-term R C L Q R K I T G E P D N N R S T S V E L T G D P N K T R G A P E A L I A N S G E P W S P S Y L G P T S N N H S K K G H C H Q E P A S L E K Q L G C C I E C-term D D F I A K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F V M D Y Y V R G D I P C R L V L F M F A M N R Q G S I I F L T V V A V D R Y F R V V H S N W T A A I I S C L L W G I T V G L T V H L L K K K R W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R K I K R A I T F I M V V A I V F V I C F L P S V V V R I H I F W L L H T S V Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T F P N F L I N
Helix box plot — Download: PNG | SVG G N G L L G F I F E L G L V P P L V K A 1 F N L A V A D F L L I I C L P F V M D Y 2 V T L F I I S G Q R N M A F M F L V L R 3 A A I I S C L L W G I T V G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I H 6 V P D L M S N M Y T F S L T I F F A L 7

GPCRdb(A)
GPCRdb(A)
HCA3 receptor
TM2
2x60 2.60x60 V83
ECL1
23x50 23.50x50 W93
TM3
3x29 3.29x29 L104
3x32 3.32x32 F107
TM7
7x38 7.39x38 L280
7x42 7.43x42 Y284