PDB
9KFT
Resolution
3.1 Å
Released
Nov. 12, 2025
Receptor
FPR1
Class
A
Species
Homo sapiens
Ligand
fMLFC peptide
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
fMLFC peptide F81 2.60x60 TM2 hydrophobic
fMLFC peptide F102 3.29x29 TM3 hydrophobic
fMLFC peptide D106 3.33x33 TM3 polar (charge-assisted hydrogen bond)
fMLFC peptide L109 3.36x36 TM3 polar (hydrogen bond with backbone)
fMLFC peptide L109 3.36x36 TM3 Van der Waals
fMLFC peptide F110 3.37x37 TM3 Van der Waals
fMLFC peptide F110 3.37x37 TM3 hydrophobic
fMLFC peptide V113 3.40x40 TM3 Van der Waals
fMLFC peptide F178 45.52x52 ECL2 hydrophobic
fMLFC peptide F178 45.52x52 ECL2 Van der Waals
fMLFC peptide R201 5.38x39 TM5 polar (charge-assisted hydrogen bond)
fMLFC peptide R205 5.42x43 TM5 Van der Waals
fMLFC peptide G209 5.46x461 TM5 Van der Waals
fMLFC peptide Y257 6.51x51 TM6 polar (hydrogen bond)
fMLFC peptide A264 6.58x58 TM6 hydrophobic
fMLFC peptide A264 6.58x58 TM6 Van der Waals
fMLFC peptide I268 ECL3 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 T H ICL1ECL1 G H W P F ECL1ICL2 P V W T Q N H R ICL2ECL2 T T V P G K T G T V A C T F N F S P W T N ECL2ICL3 L I K S ICL3ECL3 I R E L L Q G M ECL3N-term M E T N S S L P T N I S G G T P A V N-termC-term P A S L E R A L T E D S T Q T S D T A T N S T L P S A E V E L Q A K C-term S A G Y L F L D I I T Y L V F A V T F V L G V L G N G L V I W V A G F R M T V T T I S Y L N L A V A D F C F T S T L P F F M V R K A M G G W F L C K F V F T I V D I N L F G S V F L I A L I A L D R C V C V L H T V S L A K K V I I G P W V M A L L L T L P V I I R V D P K E R I N V A V A M L T V R G I I R F I I G F S A P M S I V A V S Y G L I A T K I H K Q G S R P L R V L S F V A A A F F L C W S P Y Q V V A L I A T V R Y K E I G I A V D V T S A L A F F N S C L N P M L Y V F M G Q D L I H F R E R A L
Helix box plot — Download: PNG | SVG G N G L V G L V F T V A F V L Y T I I D 1 L N L A V A D F C F T S T L P F F M V R 2 L A I L F V S G F L N I D V I T F V F K 3 A K K V I I G P W V M A L L L T L P V 4 Y S V A V I S M P A S F G I I F R I I G R 5 S F V A A A F F L C W S P Y Q V V A L I 6 M P N L C S N F F A L A S T V D V A I 7

GPCRdb(A)
GPCRdb(A)
FPR1
TM2
2x60 2.60x60 F81
TM3
3x29 3.29x29 F102
3x33 3.33x33 D106
3x36 3.36x36 L109
3x37 3.37x37 F110
3x40 3.40x40 V113
ECL2
45x52 45.52x52 F178
TM5
5x39 5.38x39 R201
5x43 5.42x43 R205
5x461 5.46x461 G209
TM6
6x51 6.51x51 Y257
6x58 6.58x58 A264