PDB
9LFC
Resolution
3.6 Å
Released
May 27, 2026
Receptor
B1
Class
A
Species
Homo sapiens
Ligand
CHEMBL410363
Function
Antagonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL410363 N28 N-term polar (hydrogen bond)
CHEMBL410363 G89 2.56x56 TM2 Van der Waals
CHEMBL410363 L90 2.57x57 TM2 hydrophobic
CHEMBL410363 W93 2.60x60 TM2 hydrophobic
CHEMBL410363 W93 2.60x60 TM2 Van der Waals
CHEMBL410363 F101 ECL1 Van der Waals
CHEMBL410363 F101 ECL1 hydrophobic
CHEMBL410363 I113 3.28x28 TM3 Van der Waals
CHEMBL410363 N114 3.29x29 TM3 Van der Waals
CHEMBL410363 I117 3.32x32 TM3 Van der Waals
CHEMBL410363 I117 3.32x32 TM3 hydrophobic
CHEMBL410363 R176 ECL2 polar (charge-assisted hydrogen bond)
CHEMBL410363 L184 ECL2 Van der Waals
CHEMBL410363 I190 45.51x51 ECL2 Van der Waals
CHEMBL410363 I190 45.51x51 ECL2 hydrophobic
CHEMBL410363 L191 45.52x52 ECL2 Van der Waals
CHEMBL410363 L191 45.52x52 ECL2 hydrophobic
CHEMBL410363 R202 5.38x39 TM5 polar (charge-assisted hydrogen bond)
CHEMBL410363 Y266 6.51x51 TM6 Van der Waals
CHEMBL410363 Y266 6.51x51 TM6 polar (hydrogen bond)
CHEMBL410363 E273 6.58x58 TM6 polar (charge-assisted hydrogen bond)
CHEMBL410363 F276 6.61x61 TM6 hydrophobic
CHEMBL410363 E287 7.28x27 TM7 polar (charge-assisted hydrogen bond)
CHEMBL410363 D291 7.32x31 TM7 Van der Waals
CHEMBL410363 L294 7.35x34 TM7 Van der Waals
CHEMBL410363 Q295 7.36x35 TM7 polar (hydrogen bond)
CHEMBL410363 Q295 7.36x35 TM7 Van der Waals
CHEMBL410363 N298 7.39x38 TM7 polar (hydrogen bond)
CHEMBL410363 N298 7.39x38 TM7 Van der Waals
CHEMBL410363 F302 7.43x42 TM7 Van der Waals
CHEMBL410363 F302 7.43x42 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R R Q L ICL1ECL1 F N W P F ECL1ICL2 P M A S R R Q ICL2ECL2 S I Q A V P D L N I T A C I L L L P ECL2ICL3 C G G R K D ICL3ECL3 A V R ECL3N-term M A S S W P P L E L Q S S N Q S Q L F P Q N A T A C D N A N-termC-term Q C T P K S L A P I S S S H R K E I F Q L F W R N C-term P E A W D L L H R V L P T F I I S I C F F G L L G N L F V L L V F L L P N V A E I Y L A N L A A S D L V F V L G L P F W A E N I W N Q G A L L C R V I N G V I K A N L F I S I F L V V A I S Q D R Y R V L V H Q R R R Q A R V T C V L I W V V G G L L S I P T F L L R H E A W H F A R I V E L N I L G F L L P L A A I V F F N Y H I L A S L R T R E E V S R T R S K T T A L I L T L V V A F L V C W A P Y H F F A F L E F L F Q V Q G C F W E D F I D L G L Q L A N F F A F T N S S L N P V I Y V F V G R L V W E F R T K L Y K
Helix box plot — Download: PNG | SVG L N G L L G F F C I S I I F T P L V R H 1 A N L A A S D L V F V L G L P F W A E N 2 A V V L F I S I F L N A K I V G N I V R 3 A R V T C V L I W V V G G L L S I P T 4 N F F V I A A L P L L F G L I N L E V I R 5 L T L V V A F L V C W A P Y H F F A F L 6 V P N L S S N T F A F F N A L Q L G L 7

GPCRdb(A)
GPCRdb(A)
B1 receptor
TM2
2x56 2.56x56 G89
2x57 2.57x57 L90
2x60 2.60x60 W93
TM3
3x28 3.28x28 I113
3x29 3.29x29 N114
3x32 3.32x32 I117
ECL2
45x51 45.51x51 I190
45x52 45.52x52 L191
TM5
5x39 5.38x39 R202
TM6
6x51 6.51x51 Y266
6x58 6.58x58 E273
6x61 6.61x61 F276
TM7
7x27 7.28x27 E287
7x31 7.32x31 D291
7x34 7.35x34 L294
7x35 7.36x35 Q295
7x38 7.39x38 N298
7x42 7.43x42 F302