PDB
9M0R
Resolution
2.5 Å
Released
July 23, 2025
Receptor
NPFF1
Class
A
Species
Homo sapiens
Ligand
Neuropeptide VF
Function
Agonist
Reference
10.1016/J.CELREP.2025.116160

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Neuropeptide VF V127 3.36x36 TM3 hydrophobic
Neuropeptide VF W204 45.51x51 ECL2 hydrophobic
Neuropeptide VF T217 5.39x40 TM5 Van der Waals
Neuropeptide VF T217 5.39x40 TM5 polar (hydrogen bond)
Neuropeptide VF W287 6.52x52 TM6 Van der Waals
Neuropeptide VF W287 6.52x52 TM6 hydrophobic
Neuropeptide VF L290 6.55x55 TM6 hydrophobic
Neuropeptide VF L290 6.55x55 TM6 Van der Waals
Neuropeptide VF T307 7.31x30 TM7 Van der Waals
Neuropeptide VF F311 7.35x34 TM7 hydrophobic
Neuropeptide VF F311 7.35x34 TM7 Van der Waals
Neuropeptide VF H315 7.39x38 TM7 polar (hydrogen bond)
Neuropeptide VF H315 7.39x38 TM7 Van der Waals
Neuropeptide VF F319 7.43x42 TM7 Van der Waals

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R H M H ICL1ECL1 G W P F ECL1ICL2 P F R E K L ICL2ECL2 T V T R E E H H F M V D A R N R S Y P L Y S C W E A W P E K ECL2ICL3 G G E E A ICL3ECL3 Q L S A P Q L ECL3N-term M E G E P S Q P P N S S W P L S Q N G T N T E A T P A T N L T F S S Y Y Q H T S P V N-termC-term P R P S G S H K E A Y S E R P G G L L H R R V F V V V R P S D S G L P S E S G P S S G A P R P G R L P L R N G R V A H H G L P R E G P G C S H L P L T I P A W D I C-term A A M F I V A Y A L I F L L C M V G N T L V C F I V L K N T V T N M F I L N L A V S D L L V G I F C M P T T L V D N L I T D N A T C K M S G L V Q G M S V S A S V F T L V A I A V E R F R C I V H T L R K A L V T I A V I W A L A L L I M C P S A V T L G M R R V Y T T V L F S H I Y L A P L A L I V V M Y A R I A R K L C Q A P G P A P A D P R A S R R R A R V V H M L V M V A L F F T L S W L P L W A L L L L I D Y G H L V T V Y A F P F A H W L A F F N S S A N P I I Y G Y F N E N F Q A R L C F R R G A F R A
Helix box plot — Download: PNG | SVG T N G V M C L L F I L A Y A V I F M A A 1 L N L A V S D L L V G F I C M P T T L V D 2 A V L T F V S A S V S M G Q V L G S M K 3 A L V T I A V I W A L A L L I M C P S 4 Y M V V I L A L P A L Y I H S F L V T T Y 5 V M V A L F F T L S W L P L W A L L L L 6 I P N A S S N F F A L W H A F P F A Y 7

GPCRdb(A)
GPCRdb(A)
NPFF1 receptor
TM3
3x36 3.36x36 V127
ECL2
45x51 45.51x51 W204
TM5
5x40 5.39x40 T217
TM6
6x52 6.52x52 W287
6x55 6.55x55 L290
TM7
7x30 7.31x30 T307
7x34 7.35x34 F311
7x38 7.39x38 H315
7x42 7.43x42 F319