PDB
9M3S
Resolution
2.8 Å
Released
March 11, 2026
Receptor
taar13a
Class
A
Species
Danio rerio
Ligand
histamine
Function
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
histamine D112 3.32x32 TM3 polar (charge-assisted hydrogen bond)
histamine L113 3.33x33 TM3 hydrophobic
histamine T116 3.36x36 TM3 polar (hydrogen bond)
histamine T116 3.36x36 TM3 Van der Waals
histamine F194 ECL2 Van der Waals
histamine D202 5.42x43 TM5 polar (charge-assisted hydrogen bond)
histamine T206 5.46x461 TM5 Van der Waals
histamine W269 6.48x48 TM6 Van der Waals
histamine F272 6.51x51 TM6 aromatic (edge-to-face)
histamine F272 6.51x51 TM6 Van der Waals
histamine F273 6.52x52 TM6 hydrophobic
histamine F273 6.52x52 TM6 Van der Waals

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Snake plot — Download: PNG | SVG
ICL1 K Q L Q ICL1ECL1 C W Y ECL1ICL2 P L Q Y P T R I ICL2ECL2 K A N V E G L E E Y I E S I Y C M G H C S L L F ECL2ICL3 P N E N ICL3ECL3 N F S T ECL3N-term M D L S S Q E Y D P S Q F C F P A V N N S C L K G T H N-termC-term R R I F E P N S S D I N V F T V C-term H V S T Q T V V Y L I L A S A M T V T I L G N S V V I I S I A H F T P T N I L V M S L A L A D L L L G L V V M P F S M I R S V D G Y G E T F C M L H S T F D L F L T S V S I L H L V C I A V D R H Q A V C Y T I S V A W V M V M I S W T L I A I Y S Y G L V Y S S K L W S V L D T F I T F F F P S C I M V G L Y I R I F V V A N K H A R V I T E A N E N V F K S S R R S E R K A A K T L G I V V G A F I I C W L P F F I N S L M D P Y I P V A L F D A F V W L G Y I N S T I N P I I Y G F F Y P W F Y L I R K T L I T
Helix box plot — Download: PNG | SVG S N G L I T V T M A S A L I L Y V V T Q 1 M S L A L A D L L L G V L V M P F S M I R 2 C V L H L I S V S T L F L D F T S H L M 3 A W V M V M I S W T L I A I Y S Y G L V 4 Y L G V M I C S P F F F T I F T D L V S W 5 G I V V G A F I I C W L P F F I N S L M 6 I P N I T S N I Y G L W V F A D F L A 7

GPCRdb(A)
GPCRdb(A)
taar13a
TM3
3x32 3.32x32 D112
3x33 3.33x33 L113
3x36 3.36x36 T116
TM5
5x43 5.42x43 D202
5x461 5.46x461 T206
TM6
6x48 6.48x48 W269
6x51 6.51x51 F272
6x52 6.52x52 F273