PDB
9M8V
Resolution
3.8 Å
Released
Sept. 24, 2025
Receptor
GPR3
Class
A
Species
Homo sapiens
Ligands
Function
AF64394 (A:401)
NAM
AF64394 (A:402)
NAM
Reference
—
AF64394 (A:401) AF64394 (A:402)

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Ligand Amino Acid Generic Number Segment Interaction Type
AF64394 (A:401) L128 3.44x44 TM3 hydrophobic
AF64394 (A:401) V132 3.48x48 TM3 Van der Waals
AF64394 (A:401) L136 3.52x52 TM3 Van der Waals
AF64394 (A:401) R152 4.41x41 TM4 Van der Waals
AF64394 (A:401) M156 4.45x45 TM4 Van der Waals
AF64394 (A:401) L159 4.48x48 TM4 hydrophobic
AF64394 (A:401) I208 5.53x53 TM5 Van der Waals
AF64394 (A:402) Q211 5.56x56 TM5 Van der Waals
AF64394 (A:402) A214 5.59x59 TM5 Van der Waals
AF64394 (A:402) R218 5.63x63 TM5 polar (hydrogen bond)

NGL is a WebGL based 3D viewer powered by MMTF.

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NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 P A F R ICL1ECL1 C I G ECL1ICL2 A L T Y Y ICL2ECL2 V L A W N C L D G L T T C G V V Y P L ECL2ICL3 H L ICL3ECL3 D A H S ECL3N-term M M W G A G S P L A W L S A G S G N V N V S S V G P A E G P T G P A A P L P S P N-termC-term C C S S S K I P F R S R S P S D V C-term K A W D V V L C I S G T L V S C E N A L V V A I I V G T A P M F L L V G S L A V A D L L A G L G L V L H F A A V F S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N S E T T V T R T Y V M L A L V W G G A L G L G L L P S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R L P A S H Y V A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D L W A V Q K V V C C
Helix box plot — Download: PNG | SVG A N E C S V L T G S I C L V V D W A K 1 G S L A V A D L L A G L G L V L H F A A 2 A L L S G I S A T F A M A L V G V L V L 3 T Y V M L A L V W G G A L G L G L L P 4 Y L Q L M I G F V M F F A I A L V V L H 5 A V V L G A F A A C W L P F T V Y C L L 6 I P N I M S N Y T A P L L T L Y T Y L 7

GPCRdb(A)
GPCRdb(A)
GPR3
TM3
3x44 3.44x44 L128
3x48 3.48x48 V132
3x52 3.52x52 L136
TM4
4x41 4.41x41 R152
4x45 4.45x45 M156
4x48 4.48x48 L159
TM5
5x53 5.53x53 I208
5x56 5.56x56 Q211
5x59 5.59x59 A214
5x63 5.63x63 R218