PDB
9O36
Resolution
2.3 Å
Released
April 1, 2026
Receptor
μ
Class
A
Species
Mus musculus
Ligand
Fluornitrazene
Function
Agonist
Reference
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Ligand Amino Acid Generic Number Segment Interaction Type
Fluornitrazene Y75 1.39x39 TM1 polar (charge-assisted hydrogen bond)
Fluornitrazene Y75 1.39x39 TM1 polar (hydrogen bond)
Fluornitrazene Y75 1.39x39 TM1 polar (charge-assisted hydrogen bond)
Fluornitrazene L121 2.57x57 TM2 Van der Waals
Fluornitrazene Q124 2.60x60 TM2 polar (hydrogen bond)
Fluornitrazene Q124 2.60x60 TM2 polar (charge-assisted hydrogen bond)
Fluornitrazene S125 2.61x61 TM2 Van der Waals
Fluornitrazene Y128 2.64x64 TM2 Van der Waals
Fluornitrazene D147 3.32x32 TM3 polar (charge-assisted hydrogen bond)
Fluornitrazene Y148 3.33x33 TM3 hydrophobic
Fluornitrazene Y148 3.33x33 TM3 Van der Waals
Fluornitrazene M151 3.36x36 TM3 Van der Waals
Fluornitrazene V236 5.42x43 TM5 Van der Waals
Fluornitrazene W293 6.48x48 TM6 Van der Waals
Fluornitrazene I296 6.51x51 TM6 polar (hydrogen bond)
Fluornitrazene H297 6.52x52 TM6 Van der Waals
Fluornitrazene V300 6.55x55 TM6 polar (hydrogen bond)
Fluornitrazene W318 7.35x34 TM7 Van der Waals
Fluornitrazene H319 7.36x35 TM7 polar (charge-assisted hydrogen bond)
Fluornitrazene I322 7.39x38 TM7 polar (hydrogen bond)
Fluornitrazene Y326 7.43x42 TM7 polar (hydrogen bond)

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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A G P G N I S D C S D P L A P A S C S P A P G S W L N L S H V D G N Q S D P C G P N R T G L G G S H S L C P Q T G S P S N-termC-term P T S S T I E Q Q N S A R I R Q N T R E H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M V T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G N I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I V N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L I T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
Helix box plot — Download: PNG | SVG F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I V N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7

GPCRdb(A)
GPCRdb(A)
μ receptor
TM1
1x39 1.39x39 Y75
TM2
2x57 2.57x57 L121
2x60 2.60x60 Q124
2x61 2.61x61 S125
2x64 2.64x64 Y128
TM3
3x32 3.32x32 D147
3x33 3.33x33 Y148
3x36 3.36x36 M151
TM5
5x43 5.42x43 V236
TM6
6x48 6.48x48 W293
6x51 6.51x51 I296
6x52 6.52x52 H297
6x55 6.55x55 V300
TM7
7x34 7.35x34 W318
7x35 7.36x35 H319
7x38 7.39x38 I322
7x42 7.43x42 Y326