PDB
9UAM
Resolution
3.3 Å
Released
March 18, 2026
Receptor
CysLT2
Class
A
Species
Homo sapiens
Ligand
Function
LTC4
Agonist
Reference
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Ligand Amino Acid Generic Number Segment Interaction Type
LTC4 T130 3.44x44 TM3 Van der Waals
LTC4 V134 3.48x48 TM3 Van der Waals
LTC4 F137 3.51x51 TM3 Van der Waals
LTC4 L138 3.52x52 TM3 Van der Waals
LTC4 H142 3.56x56 TM3 Van der Waals
LTC4 L147 ICL2 Van der Waals
LTC4 I219 5.56x56 TM5 hydrophobic
LTC4 C220 5.57x57 TM5 Van der Waals
LTC4 L223 5.60x60 TM5 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 Y K K S ICL1ECL1 S N W I F ECL1ICL2 P F R L L H V T ICL2ECL2 G S E Q N G S V T S C L E L N L Y K ECL2ICL3 E V P E ICL3ECL3 K V G L C ECL3N-term M E R K F M S L Q P S I S V S E M E P N G T F S N N N S R N N-termC-term G H P Q K A K T K C V F P V S V W L R K E T R V C-term C T I E N F K R E F F P I V Y L I I F F W G V L G N G L S I Y V F L Q P T S V N V F M L N L A I S D L L F I S T L P F R A D Y Y L R G G D L A C R I M S Y S L Y V N M Y S S I Y F L T V L S V V R F L A M V H S I R S A W I L C G I I W I L I M A S S I M L L D S I A K L Q T M N Y I A L V V G C L L P F F T L S I C Y L L I I R V L L K V S G L R V S H R K A L T T I I I T L I I F F L C F L P Y H T L R T V H L T T W K D R L H K A L V I T L A L A A A N A C F N P L L Y Y F A G E N L K S F K D R A L R K
Helix box plot — Download: PNG | SVG G N G L V G W F F I I L Y V I P F F E R 1 L N L A I S D L L F I S T L P F R A D Y 2 V T L F Y I S S Y M N V Y L S Y S M I R 3 A W I L C G I I W I L I M A S S I M L 4 Y C I S L T F F P L L C G V V L A I Y N M 5 I I I T L I I F L F C F L P Y H T L R T V 6 L P N F C A N A A A L A L T I V L A K 7

GPCRdb(A)
GPCRdb(A)
CysLT2 receptor
TM3
3x44 3.44x44 T130
3x48 3.48x48 V134
3x51 3.51x51 F137
3x52 3.52x52 L138
3x56 3.56x56 H142
TM5
5x56 5.56x56 I219
5x57 5.57x57 C220
5x60 5.60x60 L223