PDB
9UAN
Resolution
3.5 Å
Released
March 18, 2026
Receptor
CysLT2
Class
A
Species
Homo sapiens
Ligand
Function
LTD4
Agonist
Reference
—

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Ligand Amino Acid Generic Number Segment Interaction Type
LTD4 F137 3.51x51 TM3 hydrophobic
LTD4 H142 3.56x56 TM3 Van der Waals
LTD4 R145 ICL2 polar (charge-charge)
LTD4 L147 ICL2 hydrophobic
LTD4 I219 5.56x56 TM5 hydrophobic
LTD4 L223 5.60x60 TM5 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 Y K K S ICL1ECL1 S N W I F ECL1ICL2 P F R L L H V T ICL2ECL2 G S E Q N G S V T S C L E L N L Y K ECL2ICL3 E V P E ICL3ECL3 K V G L C ECL3N-term M E R K F M S L Q P S I S V S E M E P N G T F S N N N S R N N-termC-term G H P Q K A K T K C V F P V S V W L R K E T R V C-term C T I E N F K R E F F P I V Y L I I F F W G V L G N G L S I Y V F L Q P T S V N V F M L N L A I S D L L F I S T L P F R A D Y Y L R G G D L A C R I M S Y S L Y V N M Y S S I Y F L T V L S V V R F L A M V H S I R S A W I L C G I I W I L I M A S S I M L L D S I A K L Q T M N Y I A L V V G C L L P F F T L S I C Y L L I I R V L L K V S G L R V S H R K A L T T I I I T L I I F F L C F L P Y H T L R T V H L T T W K D R L H K A L V I T L A L A A A N A C F N P L L Y Y F A G E N L K S F K D R A L R K
Helix box plot — Download: PNG | SVG G N G L V G W F F I I L Y V I P F F E R 1 L N L A I S D L L F I S T L P F R A D Y 2 V T L F Y I S S Y M N V Y L S Y S M I R 3 A W I L C G I I W I L I M A S S I M L 4 Y C I S L T F F P L L C G V V L A I Y N M 5 I I I T L I I F L F C F L P Y H T L R T V 6 L P N F C A N A A A L A L T I V L A K 7

GPCRdb(A)
GPCRdb(A)
CysLT2 receptor
TM3
3x51 3.51x51 F137
3x56 3.56x56 H142
TM5
5x56 5.56x56 I219
5x60 5.60x60 L223