CHEMBL246639


SMILES COc1cccc(-c2cc3c(CN4CCc5cc(OC)c(OC)cc5C4)ccc(OC)c3o2)c1
InChIKey HIASAPHKGILEIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 459.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.09 6.09 6.09 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.72 7.72 7.72 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.59 5.59 5.59 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.59 5.59 5.59 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 6.09 6.09 6.09 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 7.72 7.72 7.72 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database