CHEMBL246794


SMILES COc1cc(N2CC(=O)N(c3ccc(Oc4ccccc4)cc3)C2=O)ccc1OCCN1CCCC1
InChIKey WTVQMTFZYWXSRS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MCH1 MCHR1 Human Melanin-concentrating hormone A pKi 6.79 6.79 6.79 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.06 6.06 6.06 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.43 6.43 6.43 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database