CHEMBL251975


SMILES CN1CCN(CC(=O)Nc2cc(-n3cccn3)nc(-c3ccco3)n2)CC1
InChIKey QMZAMLTVEASZQQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 367.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 7.58 7.58 7.58 ChEMBL
A2B AA2BR Human Adenosine A pKi 7.46 7.46 7.46 ChEMBL
A3 AA3R Human Adenosine A pKi 6.18 6.18 6.18 ChEMBL
A2A AA2AR Human Adenosine A pKi 8.52 8.55 8.57 ChEMBL
A1 AA1R Human Adenosine A pKi 6.57 6.57 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database