CHEMBL298875


SMILES COc1c(C(=O)N[C@@H]2CCN(Cc3ccccc3)C2)cc(Br)c2ccccc12
InChIKey UBVYCNOXGQYSRQ-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 438.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.13 5.13 5.14 ChEMBL
D3 DRD3 Rat Dopamine A pKi 8.8 8.8 8.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.92 7.92 7.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.68 7.99 8.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.6 6.84 7.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.75 6.82 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database