CHEMBL3040325


SMILES COc1cccc(Nc2nc(Cc3ccccc3)nc3c2CCNCC3)c1
InChIKey BZDGCBXVIKXHFH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.3 6.3 6.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.52 7.52 7.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.04 8.04 8.04 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.43 7.43 7.43 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.08 6.08 6.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.11 7.11 7.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.07 7.07 7.07 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.03 6.03 6.03 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.79 6.79 6.79 ChEMBL