CHEMBL256492


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)ccc1OCCF
InChIKey FKHJOYFNYFVDRF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.74 8.74 8.74 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.51 6.51 6.51 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.27 5.27 5.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database