CHEMBL303339


SMILES CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1
InChIKey HENBLLXAHPTGHX-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 214.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.77 7.29 7.82 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.6 7.71 7.82 ChEMBL
D3 DRD3 Rat Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 4.69 4.69 4.69 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 5.98 5.98 5.98 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.51 7.51 7.51 ChEMBL