CHEMBL304426


SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1
InChIKey DSEPKSLFXGYPIU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 298.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.92 7.21 7.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.89 9.38 9.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.92 8.92 8.92 ChEMBL