CHEMBL305837


SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]cc(C=O)c3c2C1
InChIKey HXXAWZFROYWOFG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database